Anatomy and Physiology Anatomy: investigates body structure the term means to dissect Physiology: investigates processes and functions Human Physiology: studies the human organism Systemic Physiology: studies body organ-systems Cellular Physiology: studies body cells
Importance of Anatomy and Physiology Understand how the body: responds to stimuli environmental changes environmental cues diseases injury
Types of Anatomy Systemic: studies body organ-systems Regional: studies body regions (medical schools) Surface: studies external features, for example, bone projections Anatomical imaging: using technologies (x-rays, ultrasound, MRI)
Structural and Functional Organization 1 Six levels from chemical to organism: Chemical: smallest level atoms, chemical bonds, molecules Cellular: cells: basic units of life compartments and organelles examples are mitochondria, nucleus Figure 1.1
Structural and Functional Organization 2 Tissues: group of cells with similar structure and function plus extracellular substances they release four broad types: Epithelial Connective Muscular Nervous Figure 1.1
Structural and Functional Organization 3 Organs: two or more tissue types acting together to perform function(s) Examples: stomach, heart, liver, ovary, bladder, kidney Figure 1.1
Structural and Functional Organization 4 Organ-System: group of organs contributing to some function for example, digestive system, reproductive system Figure 1.1
Characteristics of Life 1 Organization: functional interrelationships between parts Metabolism: sum of all chemical and physical changes sustaining an organism ability to acquire and use energy in support of these changes Responsiveness: ability to sense and respond to environmental changes includes both internal and external environments
Characteristics of Life 2 Growth: can increase in size size of cells, groups of cells, extracellular materials Development: changes in form and size changes in cell structure and function from generalized to specialized— differentiation Reproduction: formation of new cells or new organisms generation of new individuals tissue repair
Homeostasis 1 Homeostasis: maintenance of constant internal environment despite fluctuations in the external or internal environment Variables : measures of body properties that may change in value Examples of variables : body temperature heart rate blood pressure blood glucose levels blood cell counts respiratory rate
Homeostasis 2 Normal range: normal extent of increase or decrease around a set point Set point: normal, or average value of a variable Over time, body temperature fluctuates around a set point Figure 1.4
Homeostasis 3 Set points for some variables can be temporarily adjusted depending on body activities, as needed: Examples Common cause of change body temperature fever heart rate, blood pressure respiratory rate exercise
Homeostasis 4 Negative feedback is the main mechanism used homeostatic regulation. A negative feedback response involves: detection: of deviation away from set point and correction: reversal of deviation toward set point and normal range
Homeostasis 5 The components of feedback: Receptor: detects changes in variable Control center: receives receptor signal establishes set point sends signal to effector Effector: directly causes change in variable
Homeostasis 6 Figure 1.5
Negative Feedback Control of Body Temperature Figure 1.6
Homeostasis 7 Positive feedback mechanisms occur when the initial stimulus further stimulates the response system response causes progressive deviation away from set point, outside of normal range not directly used for homeostasis some positive feedback occurs under normal conditions Example: childbirth generally associated with injury, disease negative feedback mechanisms unable to maintain homeostasis
Homeostasis 8 Comparison of negative feedback and positive feedback Figure 1.7
Body Cavities 1 Thoracic cavity: space within chest wall and diaphragm contains heart, lungs, thymus gland, esophagus, trachea Mediastinum: space between lungs contains heart, thymus gland, esophagus, trachea Figure 1.13
Body Cavities 2 Abdominal cavity: space between diaphragm and pelvis contains stomach, intestines, liver, spleen, pancreas, kidneys Pelvic cavity: space within pelvis contains urinary bladder, reproductive organs, part of large intestine Figure 1.13
Serous Membranes 1 Line trunk cavities, cover organs Structure: visceral serous membrane covers organs parietal serous membrane is the outer membrane cavity - a fluid-filled space between the membranes Figure 1.14
Serous Membranes 2 Three sets of serous membranes and cavities: Membrane Cavity Pericardium around heart Pericardial cavity Pleura around lungs Pleural cavity Peritoneum around abdominopelvic cavity and its organs Peritoneal cavity