Course Overview Biology of Mammalian Cells and Tissues - Histology VIBS 443/ VIBS 602 Larry Johnson Cells Tissues Organs/systems
Objectives To make a transition from molecular events to organ systems. To have classical histology merged with modern cell biology. To learn technical skills - new types of vision - using the light microscope and electron microscope.
Objectives To learn the relationship between cell structure and cell function, and how organ architecture facilitates its function. To learn normal histology as a prerequisite for understanding pathology. To learn how to communicate and have fun with histology.
Materials Laboratory notebook file, questions on eCampus p ools, study guides, and items to identify Course schedule Computers are needed to view histology images, electron micrographs, and files PowerPoint slides to introduce each laboratory, conference ( vibs histology Youtube link), and lectures ( eCampus )
To view the Images files, You will need to bring you own device to connect to the online images
Visit eCampus for class materials
Where you upload: Writing assignments and Preparative homework
Goodies, Schedule with lecture outline/lab exercises, and lecture PPTs
Goodies
We have 5 study aids for your use
http://peer.tamu.edu/histologylectures.asp
Lecture PPTs available all the time Lecture PPTs
Materials Lecture outlines, laboratory exercises, word slides, and study guides for each lecture. [Note that some of these materials are modified from copyrighted textbooks (see last page for original sources) and should not be copied for non-personal use.] Evaluation forms - may be returned in at the end of the course
Materials Textbooks Junqueira’s Basic histology Text & Atlas by Anthony L. Mescher 13e (ISBN 978-0071440912) Earlier versions will likely work too as the textbook materials will be used as a supplement source of information.
Organization Cell Biology - Tissues - Organs - Organ Systems Lectures: (26) Begin usually at 10:20 A.M. The objective of lectures is to learn about structure - function relationships and fundamental concepts. Laboratories: written up in manual to be followed along at lab time and continued if needed during discussion time on Fridays. Objective of labs are to learn cell and tissue appearance and function. Subject matter of laboratories usually will be that material covered in lecture the same day. Extra but not required Conferences : (10) To develop conceptual thinking for problem solving . We will not go over these, but they are written as question in the manual and introduction to each on eCamous
Organization Preparative homework allows the student to become familiar with the subject of the lecture prior to the lecture period. Preparative homework (25 sets total) is due at 10:00 AM prior to the lecture on the day that that subject matter is covered in the lecture. PPTs for lectures are available at all times
Organization The homework will consist of a list of 3 to 5 structures or structural features unique or specifically characteristic of cells, tissues, organs, or organ systems covered in the lecture that day, and one/two sentence(s) for each describing how these structures or structural features contribute to the unique function of that given cell, tissue, organ, or organ system . Possibly, a randomly-selected subset of homework will be graded; however, all homework submitted on time will be recorded.
Parts of course will be FLIPPED for more class time discussions. You will watch short videos in preparation for class.
Lab introductions – to set up the observation of images as directed within the lab manual Introductions to conferences
Lab introductions – to set up the observation of images as directed within the lab manual Introductions to conferences FLIP = Floating Instrument Platform
Exams: Quiz to test all materials covered since last quiz or didactic test Practical exams to test concepts and identifications Didactic exams to test everything
Writing Assignments Term Paper Objectives To advance understanding of medical topics as they relate to real-world situations To improve communication skills of students in medical fields To improve awareness of issues related to common diseases
Writing Assignments Term Paper Prompt Choose one of the lecture topics about which to compose your essay. Using the attached sample as a guide, write about issues relating to your topic. Assume this will be published in a scientific journal and will be read by your professional colleagues. Use outside sources, which should be cited correctly at the end of the paper, and describe your opinion concerning this topic and its implications to the medical field. The final product should be 2,000+ words (not to exceed 3,500 words), typed and double-spaced, in Times New Roman, with 1” margins. Be sure to include the title of the discussion conference in the paper and a list of your sources at the end. If you use a direct quotation, you must correctly cite it in the paper.
Writing Assignments Conference essay portion of midterm and final exams Conferences essays will consist of short answers and essays describing experiments, procedures, expected findings, and conclusions.
Writing Assignments Submittals on eCampus The following will be due throughout the semester (see class schedule above). Feedback will be given at each step with a final grade for the final draft. Outline Description First Draft Second Draft Final Draft Grading of the term paper Outline and Description: completion First Draft: 30 Second Draft: 50 Final Draft: 170 Term Paper 250 points__________________________________________________________ Total Percent of Course: 25% 250/1000 points ********* Writing part of class must be passed to pass the course ***********
Grading Point distribution Point Values Preparative homework 100 Quiz (6) every other week (50 points each – you may drop two)) 200 Term paper writing 250 Mid term Practical portion 100 Didactic portion 100 Final Practical portion 100 Didactic portion 100 ----------------------------------------------------------------------- Total 1000
Organization Student participation in class and student enhancement of the objectives of the course are encouraged and may pay off in borderline cases. Scholastic dishonesty including plagiarism as defined at the TAMU Web Site (http://student-rules.tamu.edu/rules20.htm) will not be allowed. Grades may be curved at the end of the semester.
Getting Started in the Laboratory Light microscope parts Kohler illumination page 28 field diaphragm
Focus on the tissue specimen using the course/fine focus knobs. 2. Close the field diaphragm. Focus the condenser (e.g. , image of the closed field diaphragm) on the specimen using the condenser height adjustment knob. Center the condenser (e.g., image of the field diaphragm) with the two condenser centering knobs so that the light passing through the opening of the field diaphragm is concentric with the peripheral edges of view. Open the field diaphragm so that field diaphragm is just outside of view. Kohler illumination
Kohler illumination Focus on the tissue. Close the field diaphragm. Focus the condenser. Center the condenser 5. Open the field diaphragm. Focus on the tissue Close the field diaphragm Focus the condenser Center the condenser Open the field diaphragm 1 3 2 4 5
Cartilage growth in endochondral bone formation of the Fetal finger 220
Fingertip, monkey - sweat glands and ducts among Pacinian corpuscles 105