23.hematinics

Hematinics

1. HAEMATINIC
S

2. Haematinics
Agents required in the formation of blood
Include : iron, vitamin B
12
and folic acid

3. Oral preparations:
1. Ferrous sulfate
2. Ferrous gluconate
3. Ferrous fumarate
Parenteral preparations:
1. Iron dextran
2. Iron sorbitol citric acid complex

4. Adverse effects of oral iron
GIT : epigastric pain, nausea, vomiting
metallic taste, constipation/ diarrhea
Prevention: Taken immediately after or with
meals
Staining of teeth (liquid formulations)
Blackening of stools

5. Adverse effects of parenteral iron :
 Pain at site of injection
 Pigmentation of skin, abscess
Fever, headache, joint pain
 Hypersensitivity reaction

6. Therapeutic uses of iron
1. Treatment of iron deficiency anaemia

2. Prophylaxis of iron deficiency anaemia
Pregnancy, lactation
Infants and growing children
Professional blood donors

7. Preparations:
Cyanocobalamin
Hydroxocobalamin
Methylcobalamin


Vitamin B
12

8. Uses of vitamin B
12
1.Treatment and prophylaxis of vitamin B
12
deficiency (megaloblastic anemia)

2. Vit B
12
injection in pernicious anemia
(condition where Vit B
12
is not absorbed from
the stomach)

9. FOLIC ACID
Preparations
Folic acid
Folinic acid : active form of folic acid

10. Therapeutic uses
- Megaloblastic anemias due to folic acid
deficiency
- As supplement during pregnancy
- To prevent deficiency:
Malabsorption syndromes
Antiepileptic therapy
Methotrexate toxicity

11. THANK YOU