3D_c2dd6554d97db3074a3abb598ea6fb7f_340.606-Lec-CC-D-Twose.pdf

Systematic review and meta analysis

1. Documenting Your Search and Conclusions
Section D

2. Bibliographic Management Software
! Download and store results of electronic searches in Endnote
- Also ProCite, Reference Manager (same company), and RefWorks
- QUOSA: another option for post-search automated full-article
retrieval
! Use fields to store key information (e.g., how record is identified,
reason for exclusion)
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3. Document Your Findings
! When you searched (month/
year)
! Where you searched
- Electronic databases
- Hand-searches
- Trial registers
- Communications with
experts and industry
- Bibliographies, etc.
- Internet
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! How you searched
- Search strategies
! What you found
- PRISMA flow diagram

4. No. records identified
through database searching
No. additional records identified
through other sources
No. records
screened
No. studies included
in qualitative synthesis
No. full-length articles
assessed for eligibility
No. records after
duplicates removed
No. records excluded
No. full-length articles
excluded, with reasons
No. studies included
in quantitative synthesis
Source: Liberati, et al. (2009). BMJ. Or: www.prisma-statement.org/.
PRISMA Flow of Information
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5. Citations in Reference Lists
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Source: Fergusson, D., Glass, K. C., Hutton, B., & Shapiro, S. (2005). Randomized controlled trials of aprotinin in cardiac
surgery: could clinical equipoise have stopped the bleeding? Clin Trials, 2(3), 218–229; discussion 229–232.

6. Citations in Reference Lists
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Source: Fergusson, D., Glass, K. C., Hutton, B., & Shapiro, S. (2005). Randomized controlled trials of aprotinin in cardiac
surgery: could clinical equipoise have stopped the bleeding? Clin Trials, 2(3), 218–229; discussion 229–232.

7. Conclusions
! Create a comprehensive, sensitive search
! Develop a search strategy for electronic database searching using an
iterative approach, starting with your question/PICO
! Use all electronic and “hand” resources
! Document when, where, and how you searched and what you found
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