Preoxygenation • Goal: prolong safe apnea time (denitrogenation) • Use 100% O₂ via nonrebreather or BVM with PEEP valve • For critically ill: consider NIV or HFNC (15 L/min+) • Apneic oxygenation: nasal cannula 15 L/min during attempt
Induction Agents • Etomidate: 0.3 mg/kg (hemodynamically stable, minimal BP drop) • Ketamine: 1–2 mg/kg (bronchodilator, supports BP, ↑ secretions) • Propofol: 1–2 mg/kg (reduces BP, use cautiously in shock) • Midazolam: slower onset, not preferred for RSI
Optimization During Intubation • Position: ear-to-sternal notch, sniffing position if no c-spine injury • Apply external laryngeal manipulation (BURP) if poor view • Limit attempts to <30 seconds • Confirm visualizing cords before passing tube • If difficulty: switch technique early (VL → DL or vice versa)
Troubleshooting Failed First Pass • Reoxygenate between attempts (BVM with PEEP or HFNC) • Reassess position, blade size, suction, and secretions • Use bougie: tactile clicks and hold-up sign confirm tracheal entry • Change operator or device if repeated difficulty
Rescue & Difficult Airway • If cannot intubate but can ventilate → use supraglottic airway (LMA, i-gel) • If cannot ventilate nor intubate → perform surgical airway (cricothyrotomy) • Have a clear 'Plan B' before first attempt • Early call for anesthesia or ENT if complex anatomy
Confirmation & Post-Intubation • Primary confirmation: end-tidal CO₂ waveform • Secondary: chest rise, bilateral breath sounds, no gastric sounds • Secure tube at 22–24 cm (men), 20–22 cm (women) • Post-intubation sedation: propofol, midazolam, fentanyl infusion
Key Takeaways • Preparation and anticipation are the foundation of success • Prioritize oxygenation over speed or first-pass success • Choose agents based on hemodynamic profile • Always have a backup airway plan and equipment ready • Practice improves speed, safety, and confidence