An effective tretment of warts in cattle by using autogenous vaccine copy

case study-papillomatosis in cattle

1. An Effective Treatment of warts in cattle by using
Autogenous vaccine
Dr.M.Govindharaja Bhaskar
Veterinary Assistant Surgeon
Veterinary Dispensary
Department of Animal Husbandry,
Andhra Pradesh


Abstract
A case of Bovine Papillomatosis and its treatment with autogenous
vaccine is presented. Vaccine is prepared from the samples collected from
older warts under aseptical condition minced and suspended in 10 percent
formalin kept overnight. Allow the suspension pass through muslin cloth.
Extract collected was suspended in normal saline solution and triturated it
further and finally made suspension was once again filtered through
muslin cloth strepto-pencillin @ 2mg/ml added to the suspension.the
animal was treated with a dose of 10 ml subcutaneously and revaccinated
at 7 days interval for 6 weeks. This treatment results in sloughing of the
warts from body. Animal recovered completely in 6 weeks.


Key words: Bovine Papilloma virus, autogenous vaccine
____________________________________________________________
INTRODUCTION
Bovine Papillomatosis (BP) is a cutaneous contagious disease of cattle
occurring in all age groups, manifested in the form of warts/papillomoe on
the skin caused by Bovine Papilloma Virus (BPV).
Papillomatous growths usually found around the eye, mouth, ears, on the
side of neck, jaw, shoulders and on the udder. Infection by bovine
Papillomatous virus occurs as a result of multiplication of the virus in
basal cells leading to the warts formation.
Warts are four most common types are squat, flat, tag and pedunculated.
These warts are less harm and disappear spontaneously over long period of
time. Warts are usually benign. Infection usually results in weight loss and

2. retarded growth; lesions on mammary gland interfere with milking leading
to reduction in milk yield. Due to cauliflower like growths on the skin, its
value also deteriorated thus the disease can lead to serious economic loss if
not diagnosed and treated early. Warts may vary in size from pea sized to
tennis ball cauliflower like growth. This in later stages may spread to
entire body as numerous nodules or large masses which are either hard or
soft to touch.
The present clinical report describes the use of an autogenous vaccine as a
treatment for infectious Papillomatosis.
MATERIAL AND METHOD
During June 2016, a two and half year HF cross bred heifer suffering from
severe generalized Papillomatosis was presented to Veterinary Dispensary
Yerravaripalem, Chittor district of AP.the animal has multiple Papillomoe
varying in size from 0.5cm to 3cms in diameter disseminated on around
the eye, jaws, sides of the neck, ears, shoulder and on the abdomen.

PREPERATION OF AUTOGENOUS VACCINE
Older growth was selected and prepared aseptically; sample was collected
from older warts under aseptical condition minced and suspended in 10
percent formalin kept overnight. Allow the suspension pass through
muslin cloth. Extract collected was suspended in normal saline solution
and triturated it further and finally made suspension was once again
filtered through muslin cloth strepto-pencillin @ 2mg/ml added to the
suspension. The animal was treated with a dose of 10 ml subcutaneously
and revaccinated at 7 days interval for 6 weeks.

3. DAY-0


DAY-7


DAY-21

4. DAY-30


DAY-35



RESULTS
Autogenous vaccine administration causes sloughing off the warts from
the affected areas. Regression starts at about 10 days after the beginning of
the treatment and in 6 weeks all warts disappears and the animal shows
complete recovery.

DISCUSSION
Although papillomas are usually benign its treatment was a challenge to
the field veterinarians. Different treatment methods have been adopted to
treat the disease. Surgical intervention may be possible if less area was

5. involved. Under large area invasion surgical correction was not possible.
Effective medicines for warts are not available. The animal which was
selected for the present study had long lasting multiple nodules without
showing any signs of regression.treatement with autogenous vaccine
showed 97.5% efficiency.

Summary
Warts in cattle effectively treated by using Autogenous vaccine.
Acknowledgement
Author like to extend thanks to the support of cattle owners
References
1. Smith, B.P.(2002)Large Animal Internal Medicine.3
rd
Ed.Mosby
Inc.pp1211-1212.
2. Sreeparvathy, M., Harish.C, and Anuraj.K.S.(2011) Autogenous
Vaccination as a treatment method for bovine Papillomatosis.
Journal of Livestock science 2:38-40