Antibiotics used for typhoid fever

Antibiotics used for typhoid fever according to local culture sensitivity test, Iraqi national antimicrobial guidelines & other references

1. DRUG INFORMATION CENTRE ALAA FADHEL ALWAZNI

Antibiotics of choice for Typhoid Fever (Salmonellosis)
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* Best antibiotic regimen according to the Iraqi national antimicrobial guideline,
1
st
Ed 2020
Regimen Duration Notes
Ciprofloxacin 15mg/kg/day

5-7 days ceftriaxone changed to oral
cefixime when pt. is afebrile to
finish total 14 days duration Cefixime 20mg/kg/day

7-14 days
Azithromycin 8-10mg/kg/day

7 days
Ceftriaxone 75mg/kg/day ±
azithromycin 8-10mg/kg/day

14 days
7 days
Co trimoxazole 960mg * 2 14 days

*Salmonella bacterial isolates from our bacteriology laboratory showed
sensitivity to these antibiotics
Red cells include bacteria intrinsic resistant antibiotic
2018 2019 2020
Salmonella bacterial species
Salmonella spp. Salmonella typhi Salmonella paratyphi
No Bacterial isolate yet
6/2020

penicillin
cefoxitine
gentamycin
azithromycin azithromycin azithromycin
ciprofloxacin ciprolfoxacin ciprolfoxacin
levofloxacin levofloxacin levofloxacin
Imipenem
chloramphenicol chloramphenicol chloramphenicol
co trimoxazole co trimoxazole co trimoxazole
tetracycline tetracycline

2. DRUG INFORMATION CENTRE ALAA FADHEL ALWAZNI

* Medscape website antibiotic of choice in USA
Antibiotic
regimen
Administration Severity of
infection
Area of bacterial
strain
Ciprofloxacin oral Uncomplicated
infections
infection
acquired from
bacterial
strains of
Middle East
Ofloxacin
Cefixime
Amoxicillin
Co trimoxazole
Azithromycin
Ciprofloxacin Intravenous complicated
infections
Ofloxacin
Ceftriaxone
Cefotaxime
Ampicillin
Cotrimoxazole