Antihypertensive Drugs.pptx

Antihypertensive drugs

1. Antihypertensive Drugs

2. Hypertension Hypertension or high blood pressure is one of the most common worldwide disease among humans It is also the major risk factors for coronary heart disease, stroke and many other diseases

3. Prevalence of Hypertension An estimated 1.28 billion adults aged 30-79 years worldwide have hypertension, most (two-thirds) living in low- and middle-income countries Estimated 46% adults with hypertension are unaware of their condition Less than half of the adults (42%) with hypertension are diagnosed and treated Approximately 1 in 5 adults (21%) with hypertension have it under control India ranked 193rd for women and 170th for men in the rate of hypertension diagnosis among 200 countries India’s treatment rate is lower than nearly 80% of all countries Between 60% and 70% of men and women in the country are unaware of their condition due to lack of awareness

4. Types of Hypertension

5. Signs And Symptoms

6. Causes Of Hypertension

7. What Is Systolic And Diastolic BP

8. Classification Of Hypertension

9. Complications Of Hypertension

10. Correct Posture To Measure Blood Pressure

11. Diagnosis Of Hypertension

12. Non-Pharmacological Management Of Hypertension

13. Pharmacological Management Of Hypertension

14. RAAS Mechanism

15. How does Olmesartan works? Angiotensin II leads to : Increase in vasoconstriction Increase in Aldosterone secretion Sodium and fluid retention Increase in oxidative stress

16. Beta-Blockers Drugs which inhibit adrenergic response mediated by beta receptors Decreases the heart rate Decreases the cardiac output Lowers the blood pressure Makes the heart beat more slowly and with less force

17. Beta Receptors

18. Bisoprolol Most potent Beta1 selective- Beta blocker Has highest level of Beta1 selectivity By blocking the heart’s Beta1 adrenergic receptors, it reduces heart rate & force of contraction of the heart, thus lowers blood pressure Effectively controls high blood pressure and angina Shows no impact on lipid parameters Does not effect blood glucose level Safe for Asthma patients

19. Bisoprolol vs Metoprolol