antimicrobial resistance a silent pandemic

ams public awareness

1. Antimicrobial Resistance – A Silent Pandemic

2. DEFINITION AMR – Microbes ( bacteria, virus, fungi ) develop the ability to defeat antimicrobials that are designed to kill them MDR - “ acquired non-susceptibility to at least one agent in three or more antimicrobial categories ”

3. W hat is the main root cause for AMR ? Rise in MDRO rate

4. Various Mechanisms of Resistance

5. ORIGIN OF MDRO’S AGAINST RESPECTIVE ANTIMICROBIALS

6. Common Phenotypes & Genotypes

7. COMMON PHENOTYPES & GENOTYPES S.no Organism Phenotype Genotype Remarks 1 S. auerus MRSA Mec -A Common in S. aureus 2 Enterococcus spp , VRE Van- A ; Van-B Common in E. faecium & faecalis 3 E.coli; K. pneumoniae ; P.aeruginosa ESBL CFX- M 4 E.coli; K. pneumoniae ; CRE NDM + OXA- 48

8. VARIOUS POSSIBILITES FOR SPREAD OF AMR

9. COMMON PATTERNS

10. Industrial Pollution – source of AMR !!!

11. ABx - Animals 3x times > humans !!!

12. Some Of The Hidden Causes For Spread Of AMR !!!

13. Clinical & Economic burden of AMR !!!

14. INFECTION & MORTALITY RATE !!!

15. Mortality rates of AMR

16. ATTENTION IS NEED OF HOUR !!!

17. Interconnected threats of AMR

18. LITERATURE

19. PREVENTIVE MEASURES

20. Tackling Antimicrobial Resistance By Below Fronts

21. IMPACT OF NEW DIAGNOSTICS

22. ALTERNATIVE TACKLING APPROACH’S

23. IPC PRACTICES

24. ENDNOTE For this emerging threat of AMR & increasing MDRO’S, AMSP alone can not be effective as we desired to be. We require a multi-disciplinary efforts & actions which includes Best IPC practices Effective Diagnostic Stewardship Rational AMSP approach Increase awareness community awareness & education. Which sums up to the idea of ONE HEALTH which is the only arsenal to combat AMR