Biodegradable_Polymers_in_Drug_Delivery_Systems.pptx

Biodegradable polymers

1. Biodegradable Polymers in Drug Delivery Systems Academic Presentation M.Pharm Level

2. Introduction Biodegradable polymers degrade within the body, releasing drugs in a controlled manner without surgical removal.

3. Types Natural: Chitosan, Alginate, Gelatin. Synthetic: PLGA, PCL, PLA.

4. Mechanism Drug release occurs via polymer degradation (hydrolysis or enzymatic action).

5. Applications Used in microspheres, nanoparticles, implants, and wound dressings.

6. Advantages Reduced toxicity, controlled release, and biocompatibility.

7. Limitations Batch variability, complex processing, and potential immune reactions.

8. Recent Advances Stimuli-responsive polymers and combination with nanotechnology for targeted delivery.

9. Conclusion Biodegradable polymers are vital for developing safe and effective drug delivery systems.

10. References 1. Jain RA. Biomaterials. 2000;21(23):2475–2490. 2. Anderson JM, et al. Adv Drug Deliv Rev. 2016;107:386–404.