Cell Cycle & Division_ Mitosis [Autosaved].pptx

cell cycle

1. Cell Division Mitosis From the Virtual Cell Biology Classroom on ScienceProfOnline.com Image: Cell Division , Wikipedia

2. Class Flow Prayer Presentation of the Class Flow Presentation of the Intende d Learning Outcome L esson Proper Recapitulation Activity No.1 Think-Pair-Share Activity No.2- “Card Mo I.Match Mo” Activity No.3- Sharing of Insights Synthesis Reflection

3. Presentation of the Science Routine

4. Cell Division Mitosis From the Virtual Cell Biology Classroom on ScienceProfOnline.com Image: Cell Division , Wikipedia

5. Intended Learning Outcomes: At the end of the session student should have: described the role of mitosis in the cell-division and cycle: defined the mitosis process; visually distinguished between the different phases of mitosis; explained the significance of mitosis in maintaining the chromosome number.

6. Review: What is Cell?

7. Review: What is Cell? Smallest structural and functional unit of an organism.

8. 1. somatic cells 2. sex cells (a.k.a. gametes, germline) SEX ually reproducing eukaryotes have two types of body cells… Image: Superficial human anatomy , Mikael Häggström& Rainer Zenz; Sperm & egg , Wikipedia Made you look! Cell Division From the Virtual Cell Biology Classroom on ScienceProfOnline.com

9. Activity No. 1- Think-Pair-Share Task: With your partner, discuss what happens when one get sunburn? How does healing happen? Source: https://www.allure.com/story/why-your-skin-peels-after-a-sunburn

10. Eukaryotic Cell Cycle – Cell grows. – DNA is replicated. – Mitotic cell division produces daughter cells identical to the parent. – Repeat. The timing of replication and cell division is highly regulated. Image: Cell cycle by Richard Wheeler From the Virtual Cell Biology Classroom on ScienceProfOnline.com

11. Image: Cell cycle by Richard Wheeler From the Virtual Cell Biology Classroom on ScienceProfOnline.com 2 major phases: Interphase (3 stages) – DNA is not condensed Mitosis (4 stages + cytokinesis) – Nuclear division & division of cytoplasm – DNA condensed Eukaryotic Cell Cycle

12. How will you describe the interphase?

13. Interphase Non-dividing state with 3 sub-stages: Gap 1 – cell grows in size – organelles replicated Synthesis – replication of DNA – synthesis of proteins associated with DNA Gap 2 – synthesis of proteins associated with mitosis Image: Cell cycle by Richard Wheeler; Interphase in Onion Cell Drawing & Photo, Source Unknown From the Virtual Cell Biology Classroom on ScienceProfOnline.com

14. Packing for the move … When the cell is not dividing… DNA molecules are in extended, uncondensed form called chromatin Cell can only replicate and transcribe DNA when it is in the extended state. When the cell is preparing for division… DNA molecules condense to form chromosomes prior to division. each chromosome is a single molecule of DNA easier to sort and organize the replicated DNA into daughter cells From the Virtual Cell Biology Classroom on ScienceProfOnline.com

15. Have you ever fallen and gotten a scrape?

16. Mitosis Division of somatic cells (non-reproductive cells) in eukaryotic organisms . A single cell divides into two identical daughter cells. Daughter cells have same number of chromosomes as does parent cell.

17. Activity No. 2- “Card Mo i.Match Mo” Task: Given the materials, how match the 2 cards on how do you think are being paired. You are given 5 mins to do it.

18. Mitosis 4 sub-phases: 1 st – Prophase 2nd – Metaphase 3rd – Anaphase 4th – Telophase followed by Cytokinesis From the Virtual Cell Biology Classroom on ScienceProfOnline.com Image: Mitosis diagram , Marek Kultys

19. What happens during…

20. 1. Prophase Three Major Events chromosomes condense spindle fibers form (spindle fibers are specialized microtubules radiating out from centrioles) 3. chromosomes are captured by spindle From the Virtual Cell Biology Classroom on ScienceProfOnline.com chromatin nucleolus nucleus centrioles condensing chromosomes

21. What happens during…

22. chromosomes align along the equator of the cell, with one chromatid facing each pole centrioles spindle fibers chromosomes 2. Metaphase Images: Metaphase drawing , Henry Gray's Anatomy of the Human Body; Metaphase Onion Cell Drawing & Photo, Source Unknown

23. What happens during…

24. 3. Anaphase sister chromatids separate spindle fibers attached to kinetochores shorten and pull chromatids towards the poles. free spindle fibers lengthen and push the poles of the cell apart Images: Anaphase drawing , Henry Gray's Anatomy of the Human Body; Anaphase Onion Cell Drawing & Photo, Source Unknown From the Virtual Cell Biology Classroom on ScienceProfOnline.com

25. What happens during…

26. 4. Telophase spindle fibers disintegrate nuclear envelopes form around both groups of chromosomes chromosomes revert to their extended state cytokinesis occurs, enclosing each daughter nucleus into a separate cell Images: Telophase drawing , Henry Gray's Anatomy of the Human Body; Telophase Onion Cell Drawing & Photo, Source Unknown From the Virtual Cell Biology Classroom on ScienceProfOnline.com

27. Cytokinesis – Plant vs. Animal Cell Plant cells undergo cytokinesis by forming a cell plate between the two daughter nuclei. Animal cells undergo cytokinesis through the formation of a cleavage furrow. A ring of microtubules contract, pinching the cell in half. From the Virtual Cell Biology Classroom on ScienceProfOnline.com Images: Telophase drawing , Henry Gray's Anatomy of the Human Body; Ciliate dividing , TheAlphaWolf; Telophase Onion Cell Photo, Source Unknown

28. Reflection Question: What will happen if MITOSIS doesn’t exist/happen? Source: https://www.allure.com/story/why-your-skin-peels-after-a-sunburn

29. Reflection Question: How significant is mitosis in maintaining the chromosome number? Source: https://www.allure.com/story/why-your-skin-peels-after-a-sunburn

30. Synthesis: Today I learned that… What made me realized is…

31. Synthesis: 2n (diploid no.of chromosomes) It has PMAT stages + Cytokinesis Same genetic information in parent cell and daughter cell. Give me another one just like the other one!

32. REFLECTION POINT? What does this lesson on mitosis tell you about? Why should you learn about mitosis?

33. Intended Learning Outcomes: At the end of the session student should have: described the role of mitosis in the cell-division and cycle: defined the mitosis process; visually distinguished between the different phases of mitosis; explained the significance of mitosis in maintaining the chromosome number.

34. THANK YOU…