Cellular and molecular pharmacology

18,667 views 184 slides Jun 08, 2022
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About This Presentation

Cellular and molecular level

Size: 45.23 MB
Language: en
Added: Jun 08, 2022
Slides: 184 pages

Slide Content

AS PER PCI REGULATIONS SEMESTER
FIRST YEAR M. PHARM,

CELLULAR AND
MOLECULAR PHARMACOLOGY

Dr. PRATAP KUMAR SAHU
Dr. PRASHANT TIWARI

A Text Book of
CELLULAR AND MOLECULAR
PHARMACOLOGY
As Per PCI Regulations
FIRST YEAR M. PHARM.

Semester 1
Also useful for B. PHARM.

Dr. Pratap Kumar Sahu

Preface

Contents

ig. 121-Smooth and rough endoplasmic recam

Functions of Endep Rete

a ep recon ‘Saath endoplamie rien

SAA

Fig. 42 Negative contac pero

Fig. LA eue controle a pan

ig LAS RUA ren trough IE o ES by DA or RNA

GDS Phase (OWA sybase pase af DNA eh

9-15: Role ap ara nga reget of lle

3 257 Gen a complex phosphors the prin

Maple choke Questions

Pals a horosomes nhumanbeng

om

ni … B

CELL SIGNALING

24 INTRODUCTION

O Comento ringers compote wth opens forthe same receptor se

(©) Competitive reversible antagoi Aragon

rl Agonist
à pari gon OÙ repos of smatre

Fig. 25: mise Atty DA) o erent ands
RECEPTOR CLASSIFICATION

Table 24: iii of os (ati) arse he eal membrane
en encarta

“abla 22 Or sbunit of prota, hair effector and funcions
poten Second Metenger Receptor Boop Agent

Rare | qye | efector Second anton

cpu mesenger

Fig, 27: Role of cAMP (receptor an, a api as second messenger on

ivi ie (NO) and cie CMP (MP)

Fi. 221: Rol of Gc AMP (AMP) s second messenger on cria muse

Time required nes

Tle 26 Some of th reine frase int receptors OTR ling

Sel protein Boceto

era PPAR)

gro domi though G tein coupled receptors (PCR.

ax

Uni. D

TOOLS AND TECHNIQUES

compita to veer fang te ge ONE
(9 Datura: On io the temperature to bout BE for about A mine te

Fo, 33: roces of eversetansriptin pol meras hin rection (RT-PCR)
lfm Quarter PER

Arnage over Agra Gt
+ Meran acammeene a pt 1940 of ONAN ng
Date of Agarose Ge

A MICROARRAY TECHNIQUE

Fi. 33 Hybridization of single stranded DNA ple) with

geen de ae sado tropas macy, Howe, no eos

ig 2.15; Mate of tinte cONA with lignes nthe miro

3. ENZYME.LINKED IMMUNOSORBENT ASSAY (ELISA)

Fig, 221: Competitive EUSA fr sample containing antibody

36 RECOMBINANT DNA TECHNOLOGY

36.4 Principle

ample

Multiplan and Exprezion of the Introduce Gene in he Host

m tase

ar GENE THERAPY
374 Appronchen for Gene Therapy

Dome Bis gene ss de td ol gen ht encodes for ing
(Lario Syndrome nino nor in pino mea due etc

demo -socted is vector sem: Ace actes us a uno ss

¿ene Dele by Non vil Systems

2. Acie Immune Define Syndrome (ADS):

aptamer:

‘QUESTIONS

Maile Coie Questions:

Subjective Questions

Anis À

GENOMICS AND
IMMUNOTHERAPEUTICS

[AND CLONING OF DISEASED GENE

ett prose Sonne re ray ve nie

(ther dogs metabolied by aceon: Acetone ako import nthe
‘xing Hem ica vts tos pope ose gant mateo woud rake the ang

Caroamszepine, phenytoin and ater: Came con 3 cue te vete
taser nung Steven loro ome fn wach a mf rash th Bere and
tether perf te kn peasy fo the der ret hs be scaled. se
CGempine und spremdegic Lie of dpi à Sted by ego
O “
‘heparin and bone marow toi: Inoue dng (iegunne mento

(a Funcional genomic dl ith funn of DIA ath eel genen NK

1) Sucia genomics: derbe the 3 mention scr of evry prot

(9 Spigenomis Eure madtestone se erable mosto on à ca ONG
haacecedelgnete medthcaon ae DNA metano and tens nackten

(6) Metagenomies The genetic mateñal recovered direct from environmental
Application

tetera Scone laoraton

(Miro quan sto rcetemins seen
(RNA sequences wes hah toughaut quencing tocar sequences is
Applications

Metho/Techngue: e
3. Protein detection wth antibodies (mmunesssys.Artboses fo pou
4. Current methods/higheouphput technologies:

Applications

“able 42: ference between Antigen contsnog preparations and
rio cont

né face br

2 Chemica mediator laos by diferent cl and th ancre

Sots (apa

Qi... D

CELL CULTURE

154 ceux cuLTuRE:

(a Phiothemest

à Gant el ander mere.
bss te cel by mere
1. Biologie Stey cabinet (SC:
Taio antike nd when handing nerve reagents and non prime cu nes
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