Cellular compound of blood from vivek ku

all information about blood and it's compounds

1. NAME:-- PRINCE KUMAR COURSE:-- B.PHARM SESSION:-- 2021 – 2025 REG NO. :-- 048 GAUTAM INSTITUTE OF PHARMACY, SAIYADBARAHI, HILSA {NALANDA} Guided by :-- KUMAR VIKRAM SIR {HOD AND ASSISTANT PROFESSER}

2. CONTENT Cellular component of blood. RBC Haemoglobin Function of haemoglobin WBC Platelates Function of platelates

3. Cellular component of blood There are three types of C.C.B. R.B.C ( Erythrocytes) W.B.C ( Leukocytes) Platelets ( Thrombocytes)  R.B.C- It contain the oxygen carrying proteins haemoglobin that gives red colour to blood. COUNT:- 4.8 million/ml in Male 4.5 million/ml in Female

4. SHAPE:- Normal biconcave SIZE:- 7.8mm 2mm thickness LIFE SPAM:- 120 days approx. It transport of oxygen and maintenance of acid base balance. It has not nucleus but has a respiratory pigment called haemoglobin. It is synthesized in bone marrow

5. * Erythropoiesis:- Process by which RBC are format in the foetus, liver, spleen and bone marrow. After birth they are formed only in the red bone marrow of sternum, rib, vertebrae ETC. Stage in the development of RBC as: 1. Proerthroblast 2. Erythroblast 3. Reticulocyte 4. Erythrocyte (RBC)

6. Proerythroblast :- It consisting a large cell having a nucleus. It doesn’t have hemoglobin initially. In the later stage hemoglobin starts appearing. Erythroblast:- It consisting a smaller cell with degenerated nucleus. But hemoglobin is fully present. Reticulocyte:- Develop from erythroblast. It contain hemoglobin and reticulum in the cytoplasm. Ertythrocyte :- It is fully develop RBC which doesn’t contain reticulum but contain adequate.

7. HAEMOGLOBIN It is the respiratory pigment of erythrocyte due to hemoglobin the colour of blood is red. It contain globin, a protein which is conjugated with hemoglobin . HB contain of body is about 158/100 ml of blood. Anemia occurs due to decrease in hemoglobin .

8. FUNCTION OF HEMOGLOBIN Transport of o2 and co2. Maintenances of acid base balance. As a source for formation of bilirubin cause of joundish

9. WBC They are colourless cells containing WBC Agranulocytes Granulocytes Neutrophils Monocytes Basophils Lymphocytes Esinophills

10. Agranulocytes :- This types of WBC don’t have a strong nucleus which is not lobed. Lymphocytes :- It is divided on to two parts on the basis of size. Small lymphocyte :- It is occurs to the extent of 2.6% of total WBC. 2. Large lymphocytes :- They are larger in size. (B) Monocytes:- It is the largest cell of WBC. It occur to the extent of 0-4% of total WBC.

11. Granulocytes :- WBC have granules in the cytoplasm. They have granules in the cytoplasm. They have nucleus which contain two or more lobes. It is divided in to three types. Neutrophils :- They contant granulars cytoplasm which stains with natural dise . Neutrophils occur to the extent of 60-70% of total WBC. Eosinophils :- It cells are slightly larger than neutrophils. The granuls are coarse and closely packed. The nucleas content two lobes. It’s count 2-4% of WBC.

12. (C) B asophilis :- They content coarse granuals as in easionphils but these granulas stain blue colour with basic dyes. It contains heparine , histamine and five- hydroxy trytamine . COUNT :- 0.5-1% of total WBC. Function Protect against infection. To aid in the repaired of injury tissue. To produce immune substances which defend against disease. To Basophils secret and articoagulant

13. Platelates Round oval cell with by convex surface. They are roughly one- fourth(1/4) of the size of RBC. Normal platelate count os 2-5 lacks per m/m of blood. Platelate don’t have nucleus but cytoplasm contains distinct granuals . It is synthesized by mega caryocytes of bone marrow.

14. FUNCTION Thromboplastin liberated from platelates is essential for clotting. They close minute lesions in the wall of blood vessels. They aid in the body’s defence machanism against bacteria. They contain some antigenic substance.