Centron Environmental Monitor

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Introducing

THE INDUSTRY LEADER

in LABORATORY SOLUTIONS

N REES
SCIENTIFIC

ANO 9001-2000

2. CENTRONEMS

‘Alarm ond dota collection hos never looked so good, so
stroightorword ond so informotionvich. Rees Scieniife's Cention
Environmental Monitoring Systems (EMS) onswer the monitoring
fond occess challenges faced in blood banks, reseorch
laboratories, lab animal reseorch fciiies ond other high-securiy
facies the world over

A single Centron system con monitor a diverse facility with muliple
locations while 1 provides instant doto access and sophisicoted
Canalis right from your desktop computer

Our continually expanding line of monitor is matched only by our
‘roundahe-clock service ond support team. Always expondoble,
visible ond network compatible, Rees systems provide you with
olarm notification, programming flexibly, rich documentation
nd a host of other features. Rees systems ore used by vitally
every major phormaceutical company worldwide and the Centon
hos become the industy’s standard in blood banks and similar
faciles.

Our full tumkey installation goes well beyond hordwore ond
software. Rees provides complete insolation including IG/OQ,
system validation, sensor calibration and thorough taining of your
personnel, os well as senice and worontes on all parts ond labor.

© Compliance
Mee! todoy’s tougher! stondors with ttl support documentation —
designed 19 meol FDA, GLP GMP AABB, AAALAC, JCAMO, USDA ond other regulator requirements
e Protection
Saleguard voluble research, ello ond produc.
© Cost Control
Reduc loses and limit your exposure fo rk.
© Time Preservation
Sove energy ond resources wih sireominad, ovlomoted dato cola.
© Integrated Access Control
‘Toll security for individuo rooms, corridos or ente li
© Centralized Alarm Systems
From local sonic 10 vic elephoned o e-ma alarm copabilies, doy and night
© Centralized Data Collection
Reducing the cost and time otsoialed wih cho or manual recordings whl increasing accuracy.
© Validation
On-ste solar validation and on ste 1Q/0G, including calibration, probe vrlicion and user Haining
Premium callin senicer voiable,
© Networking
Opera over exising TCP/IP LAN/WAN intostrctre. Muliuser, mult-biing, multi-site capability

© Report Generation
User defined repors bosed on timo, dote or ociviy Customizable reports wih Cool Repos.

3. The Ultimate Research Engine

WHAT DO WE MONITOR?
Refrigerators

Freezers and Ultra-low
Freezers

Cold Rooms
Stability Chambers

IN, Tanks

Incubators

‘Animal Holding Rooms

Clean Rooms

Centron EMS systems ore cosiy and
economically expondoble. Each central processing
station, or node, monitors up to 128 inputs, whether
hhordwired, wireless, or o combinotion of both. Each
node also controls up to 64 digital outputs. Up to
100 nodes con be networked together to form a
single system. Hordwired Muliplex-Remote Input
(MP) panels monitor up to 16 sensors each. Each
‘output pone controle up to 8 outputs

This modulor design provides you the floxbily of
purchasing all of the solutions together ot the time of
constucion/tenowoton, or string with o solution

thot meets your current needs and budget, ond
‘expanding os needed,

Wh any ype of input, rom ony numberof users, through
‘ony configuration of buildings, you con view ond print
validated reports from any touch screen or erminol with
‘oporopriate secur ceorance.

With easy-to-use Windows" bosed softwore thot offers
realtime reodings ond extensive useriendly features
‘ond benefits, Ress Scienff's Centron systems toke
‘envconmental monitoring and occess control othe ned
level in perlormence and innovation.

Winden based Centon share is bl in Ena, Spanish ond German

4. Every moment of every day
- we're watching.

A desktop version of the Canton, the Centron Tower i o small, sl.contined
unit designed 10 ft on your desktop or lob bench ond occessed using 0
stondard monitor, keyboard and mouse. Perfect fr facilities whore the wall
‘mounted enclosure ond touch-screen ore not proctcal

The Sotalite Tower ollows montosing of up to eight inputs ond is inoluable
when you have lo oversee mufipl locations with only o few monitor points a
ach ste. Operating over your existing TCP/IP WAN, the Sotlite Tower hos all
of the copobiliies of the Centron system. The Satelite Tower can operate
independently oros on addtionol node on on existing Cention EMS.

Roos Scientic's WebSerer allows users 10 sy in touch with their erica
equipment fom vinvly anywhere. Authorized users can access your fc in
real time from ony web browser. Full olor handling, input programming
copabilies ond reports ore ovolloble. The WebSener combines the
convenience of our Web$erver sofwore withthe securiy of o validotd file
server needed for GMP/GLP and other regulated fois and eliminates the
need to install he Centron sofmoro on ech network terminal

+e-Centron combines several exceptional Rees Scieniic fotures into one
convenient ond economical package. e-Centon unies Centon hordwore,
Web Access, an intemal CORW dive, Autobackup sofware, and 4 hour
batery backup; all delivered in o Tower Chassis, completo with printer,
‘monitor keyboord ond mouse, An unlimited number of authorized users con
occess the system through o standard web browser

The lotest evolution of Centron EMS, CanonSQL provides o more robust
dotabose engine operating on Oracle or SQL providing advanced and custom
reports ui Crystal Reports, Addiionl enhancements include extended 21
CAR security, independent logging rates for each input, scolable maps, and
rophicol input sous reports, WebServor software option is ovolablo to
provide acces to uses from virtually anywhere.

5. Our witless sensors wil do for monitoring what wireless
phones hove done for communication - gie you the
freadom 10 move about, Ideal fr facilis that routinely
move or rlocote equipment, these sensors allow you 10.
‘monitor equipment thot you previously could not. Great
forreseorch orimel holding rooms and clean rooms where
conduit is required os well os temporary or rented facilities
where you ore not pormited 0 run dota ies. We con
provide you wih quick ond cleoninsalaions

How does it work?
There ore three base components to he system: anses,

ater (tronsceiver) and receiver, Each unit being
‘monitored has a battery powered transmiter and a sensor.
Tico temperature applications such os refgerators and
‘reezers ore monitored using o stondord hormistor probe

Each transmite is identified by its serial number and
perotes ot 418 Me". For hose far-reaching sensors we
fer 0 repecter designed trey the sgnalto

The 900 MH Wireless Receiver connects to your Centon
node ond employs Digital Spread Spectrum (DSS)
technology to eliminote the sk of intrfarence with oer
devices ofthe some frequency For economical monitoring
of remote locations, we oe device tho! con monitor up
to 96 points and is capable of buflring dota in cose
communication 10 he system is disupted. FARM ond
2.4GH for Evopeonnstloons)

Does the entire system have to be wireless?

No. Add wieless sensor 10 existing hard wied Contron EMS
systems or go completaly wireless. For some application,
hord wiing o sensor moy moke more sense. Our wireless
systems designado work wih al of our xising Centron
systems. Our solution allows you to have the bes of both
‘words Either way, you will enoyallof the advonced network
footer, superior olorm dil outcopebilies, and secure dato
thot you have come to know and ts! from Rees Scientific.

6. Alarmed and Ready.

Centron’s alarm copabilties ore smart ond smooth
‘With local sonic, voice telephoned ond e-mail alarm
notification, Centron nodes noty the right person at
home or office, celular phone, pager or e-mail,
onytime,

Independent, Valid

‚Always within Reach

Optional cellular backup monitors Ihe primary
telephone line. I Ihe telephone line falls oF becomes
disconnected, Centron EMS will automatically oler
users ofthe four and assume all dil-out duties un
the line is restored

With Centrow’s generous telephone alarm
copobliis, (yp to 200 contocts per Cention node
organized ino 20 to 100 cal ists with doy ond night
diferencian, facilities have the convenience of
deporimentaiting ond dexcentolzing — olom
notficoton. In other words, delegote alarm handling
lo the personnel best qualified to handle the
problem. Sel up the system to decide who gels
noftied, and how. Free system administrators from
routine calls, but ollow them 10 retoin control,
accountability, ond supervisory ouhoriy. Shore the
system with multiple departments, and allow each to
hondle is own oloms, generote is own reports, ond
use its own SOPs

CCentron’s voice mail quality alarm notfcaion reports
current condition readings ond high ond low olarm
porometers, allowing you to respond by telephone
with precision ond speed. The Centron also offers
custom voice tags 10 specifically name each input in
the olorm messages.

Monitor all of your equipment and faclities

7. ated, Networked or Web based -
We have a configuration to meet your needs.

Because Centron operates over your orgonizotion’s
exising TCP/IP LAN/WAN infrostucture, access is
unlimited. You olso hove the option to access the
system over the Intemet from any computer in the
world, making i easy to monitor and control multiple
sites on your schedule,

Multi-user Networking
and Endless Divisibility

Deportmental segregation by input allows dvi
thot mokes the most sense for todoy's mult:
depormentl facilities. Restict user access based on
on individuals position, deporiment and/or
qualifications. Allow users to only view their own
inputs on facility floorplans, reports, graph, ec.

System Integrity
and Data Protection

Centon hos o comprehensive system to protect your
valuable dato and prevent sistem files. 1 has bul
in battery backup, wotchdog timer auto-reset, à dead.
system olorm, ond it automatically bocks up is own
oto, Each dota record is recorded first o it own hard
drive ond then immediately thereafter to the network
drive. If network communication is lot or the network
drive goes down, the dota wil sil be stored on the
Canon intemal drive ond immediately updote the
network drive when communication is re-established,
The Centon’ intemal hard drive allows for o neorly
infnite amount of dota buffering ond essentially
liminotes ony possibly of dota loss.

Auiobockup sofwore backs up dato to o network
locotion, loco! drive, or CD/CORW. Performing
backups in “Shared” mode allows the system to
continue to update while the backup is being
performed. An integrated CORW drive is oveileble
with Centon systems to make the process convenient,
secure ond cosy to use,

with one system - whether across the building, across town or across the country!

8. CENTRONSQL Software -

7 Security, Ease of Use, Integrity, Sharing, Quality -
l These are just a few of the data challenges facing Research
4 ‘and Manufacturing today.

Our most recent softwore advance, CentronsQL,
provides the ulimote in High Sacuriy Monitoring
CentronsQL allows the use of either Oracle or
Microsols SQL Server os Ihe dotobose engine forthe

MSDE 2000 data engine, which is sable for use os
the main data engine for small systems. Critical GP
oudi toils ond system program dota ore kept in
encrypted fies.

| == system. Centron Nodes ore equipped with Microsoft's

Copable of sophisticated graph

Advanced ond Custom Report Generation

In addition 10 rock solid tobi, industry stondord dato
formats, superior mull-user operation ond o
dromañcoly improved system overview, ContronSQL
provides a vos new omay of analysis reports thot con
be easly accessed from ony workstation. Reports con
be generated based on time, dot, activity input, event
‘ype or multiple criteria ollowing you access to who!
ou need to know, when you need to know it.

9. The next generation of reporting

CentronSQL olso offers new sofhware alarm features. Email notification now alerts users with more dei including
the input number, nome, current reading, low limit ond high limit. Additionally he number of users that can be on the

system simultaneously has increased from 10 to 501

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‘Simultaneously show detail boxes for muliple inputs on scolabl foo plans wih eus dentable icons.

In oddiion 10 monitoring your crio! equipment ond
processes, the system monitors isll. BuddyWorch
reports 1 a node goes offline, While each node is
independent ond con log dota ond alarm without
‘connectivity to the dotobose engine, DotaboseWatch
will dial out 10 report thot the node is no longer

connecting to the dolobose engine. MPX Comm ond
Bowery Alarms war if o MPX subpanel goes ofline.
These oddtional olorms allow for voice telephone
notification or e-mails 10 be mode ond all stondord
olorming functions to occur

10. Documented excellence.

‘Whether a routine reodings history or alarm history,
every Centron report gives a detailed, easy-to:
understand, accurate account thot users find
involuoble on mony leves. Al information, from oll
nodes in your system, is permanently logged to the
Readings or Event History Fies ond is encypted to
‘ensure dato integiy. You con now fully document how
los ore hondled, produce complete audit toils

istoy report, on

‘ond prin information-ich eve
demand

Event Reports allow you lo view olom,
Programming ond other events wih o
completo GMP compliant audi rail. View or

int these report selected by dote and input
nome, number, or event types. A few
examples of event types. include alarm
messages, alarm disable, alarm reset, eor
messages and program changes. You con
lso prin notes or comments that hove been
entered regording specific event.

Graphs of reodings ond daily highs, lows,
cond averages ore ovalloble a he touch of a
button. Touch grophed points on-screen ond
see complete ond occurate details.

Reports of readings, highs, lows, averages,
‘ond even moon Kinetic temperotires ore

cos produced for individvel inputs, all
inputs, or individual deporments. Automatic
dolly printouts ore an option for all reports
end graphs.

Program Change Audit Trail documents
whet o given condition was before, what it
wos changed to, who made the change,
when ond why

21 CFR 11 (Electronic Signatures)
encrypted files, dual element signing of user
ctions, intruder account lockout with
odminisrotor notification, password length
contol and expiration, comment expected
for user oclions, even online review and
opproval of records with electronic
Signatures. We've got ol.

Running Log provides documentation of oll
‘events, dlom conditions, programming ond
«colibration changes for all selected nodes.

Real-time readings ore simply o dick away.
Nome, number, sus, curent reading, ond
low ond high limits ore instonily avoiloble.

Color-coded icons display rea ime changes
ino probe's sols.

Alarm Instruction Forms thot you creoto
“appeor inthe olorm control panel ensuring the
‘proper hondling of ony olor station.

Alarm handling from real-time display of
‘probes allows you the option of entering
‘comments or notes regarding the event.

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21 CFR 11 and Validation setings

11. regulatory compliance by adding elec

12. Validation

Our systems are designed with validation in mind, Rees Scientific combines over 20 yeors of experience in
both Environmental Hordwore design ond Validation Protocol development to offer comprehensive packoges for ol
of is Environmental Monitoring ond Access Control Systems.

Volidoted site or not, the fac thot Rees Scient's Centron systems include hardware ond
sofvore validation with every insolation odds value for you. Our field engineers follow
‘on on-site IG/OQ qualficalion test protocol thot proves thot your system perles os
designed on your site. We volidee all of our sofware before release ond provide you with
9 complete test report proving effective performonce of all ¡stem functions. What this
means to you - essentially bug-tree sofware that you con tus), ond notfication of any
problems thot may be discovered. Client are welcome to review our protocols before
purchase, and oro welcome to audi our sit.

Installation
Highly skilled, factory roined installation specialist
install, program and test your new equipment

1Q/0 Testing
‘Onsite technicions perform our validation protocol,
colbrote sensors, and provide you with documented
proof of reible system funcion.

Software Validation
Softwore validation report includes test resul and
documentation to soil any inspector.

Training
On installation, our experts kein your personnel in
Conkons use, ond provide documented proof oftheir
knowledge.

‘On-Site Service
Our nationwide network of factory employed, factory
trained service engineers ensure thot your system is
well mointoined, up-to-dote, and working propery -
always. Our 24/7 technical support team answers your
questions, and our service dspotch fes problems for
you with unparalleled speed. What will YOU do when the
auditor is at YOUR door?

13. is always part of the package.

Premium Calibration Services

+ Five Point Certified Sensors with Certificate (RTD Sensors and High Accuracy Humidiy Sensors) —
In the post, many of our customers hove had o need to crify the accuracy ofthe sensor over the entire range, not
just ota single point. Rees Scientific now offers high occuracy RID ond humidiy sensors thot will be colibreied ot
5 different point. In addition tothe certificate of calibration, Rees Scientific wll ago execute a S-point loop
calibration on all inputs using cenfied sensors,

+ Three Point Calibration (available for those choosing to stay with traditional thermistor probes) -
The Three Poin! Colíbrotio tests each input at three seporote points along the range of is operation providing
added ossuronce thatthe probes will give accurate readings during high ond low alarm conditions, os wel os he
nomal operating set points.

+ Alarm Limit Testing - More commonly refered o os “Fire and Ice” testing, the Alarm Limit Testing protocol
is designed to prove tho! the sytem will indeed olarm ot each sensors set high and low alarm parameters.

‘+ Premium Sensor Calibration Protocols ore olso availabe.

Validation and Service Packages

Vol/Serv À
Bionnual On-site IG/OQ Velidation

+ Coment Software Validation monvol

+ Sofware updates lo current version

+ Calibraon of all temperature ond humidity sensor
with o NIST troceoble device

+ Onsite troning a the time ofthe validation

+ 24-hour telephone technical support

* Onsite service includes ports ond labor

Vel/Serv 8
‘Annual On-site 1Q/OQ Volidation

+ Current Software Validation manvol
Software updates 10 curent version

+ Calibration of oll temperature and humidity sensors
with o NIST traceable device

+ Onsite rining ot the time ofthe validation

+ 24-hour telephone technical support

+ Onsite service includes ports ond labor

Vol Second
Sixmonth On-site 1Q/OQ Validation

+ Current Sofware Validation menvol

+ Current IG/OQ Validation Protocol manual
Software updates to curent version

+ Calibration of oll temperature and humidity sensors
with o NIST traceable device

+ Onsite rining ct the time ofthe validation

+ 24-hour telephone technical support

+ Onsite service includes port ond labor

Service Contract

+ 24-hour telephone technical support

+ Onsite service includes ports ond lobor

14. Turn your Centron into a Security Guard.

A powerful vlidoted cord access system with the cose.
ond convenience of a Windows® based software
pplication, the Rees Scieniic Access Control system
enables you to control ond monitor access to your entre
facility rom your desktop computer.

Expendable to grow os your needs grow, the Reos
Seienfic Access Conkol system con handle up10 32,000
cards, 300 occess groups, 128 reoder groups, 16 alarm
zones, ond 32 elevator control groups. Up to 64
schedules/tine zones ond 32 holiday exceptions contol
auto lock/unlock, automatic security alarm tivation!
deochvoton, ond door access control, Eight levels of
poss code secuiy ensure thot onl the properindividuols
ore oforded the appropriate access

Eliminoting the need for seporoteolorm contol ponels,
the Roos Scientific Access Control System inegrots ol
door switches, window bugs ond motion sensors, which
con be octvoted or deactivated by. simple swipe ofthe

ccess cord. Interfacing with Rees Scientii's EMS
provides complet

environment

control of your security and

CCTV integration and photo dotobose allows you to
compare the stored photo with he view from the CCTV
camera to “See Who Enter”, ensuring thot access cords
fore being used only by the authorized cardholder.
‘Quickly locale on individual in your large, multi-site
fociliy by using the “Find a Cardholder” fecture 10
inetonly locate the lost cord reader accessed.

A voriey of user-defined reports based on timo, date,
‘ond oct including attendonce con be viewed on:
screen or printed out. They can even be set o printout
coutomatcaly.

Additional features include:

+ Anti-possback settings prevent individuals from
shoring cord access

+ Realtime on-screen simultaneous display of input
stotus on oll selected nods

+ Intorocking doors for clean rooms

+ Grophical floor plons/mops

+ Mulsuser platform runs over existing TCP/IP network.

+ Monitoring of analog inputs

+ CentonSQL software available

Feel confident and protected 24/7.

16. 1007 Veh Rood Extension
Trrton, NJ 08638

1 800 327.3141 or 609 530.1055
Invemotionol [phone]
salesaveessciantfic.com

‘wen soasciontccom

PNT207 0601