Cerebral Superficial Siderosis.pptx

Brain Superficial Siderosis

1. Cerebral Superficial Siderosis Ade Wijaya , MD – June 2023

2. Introduction Linear hemosiderin in the leptomeninges and the superficial layers of the cerebral and cerebellar cortices, the brainstem and the spinal cord Fearnley JM, Stevens JM, Rudge P. Superficial siderosis of the central nervous system. Brain. 1995;118:1051–66 . Charidimou A, Linn J, Vernooij MW, Opherk C, Akoudad S, Baron JC, Greenberg SM, Jäger HR, Werring DJ. Cortical superficial siderosis : detection and clinical significance in cerebral amyloid angiopathy and related conditions. Brain. 2015;138:2126–39. Koeppen AH, Dentinger MP. Brain hemosiderin and superficial siderosis of the central nervous system. J Neuropathol Exp Neurol. 1988;47:249–70.

3. Weidauer S, Neuhaus E, Hattingen E. Cerebral Superficial Siderosis : Etiology, Neuroradiological Features and Clinical Findings. Clinical Neuroradiology . 2022 Nov 28:1-4.

4. Classical Infratentorial Superficial Siderosis Weidauer S, Neuhaus E, Hattingen E. Cerebral Superficial Siderosis : Etiology, Neuroradiological Features and Clinical Findings. Clinical Neuroradiology . 2022 Nov 28:1-4.

5. Cortical Superficial Siderosis Weidauer S, Neuhaus E, Hattingen E. Cerebral Superficial Siderosis : Etiology, Neuroradiological Features and Clinical Findings. Clinical Neuroradiology . 2022 Nov 28:1-4.

6. Mimics of cortical superficial siderosis Cortical vein thrombosis Cortical hemorrhagic transformation in cerebral infarcts Laminar cortical necrosis (e.g . hypoxic injury, status epilepticus ) Sturge Weber syndrome Calcifying angiopathy /mineralizing microangiopathy Cockayne syndrome Weidauer S, Neuhaus E, Hattingen E. Cerebral Superficial Siderosis : Etiology, Neuroradiological Features and Clinical Findings. Clinical Neuroradiology . 2022 Nov 28:1-4.

7. Summary Linear hemosiderin in the leptomeninges and the superficial layers of the cerebral and cerebellar cortices, the brainstem and the spinal cord Supratentorial vs infratentorial Various etiology MRI brain Treatment based on etiology

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