Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)

Ciplactin (Generic Cyproheptadine Hydrochloride Tablets) are used as a therapy for Perennial and seasonal allergic rhinitis, Vasomotor rhinitis, Allergic conjunctivitis due to inhalant allergens and foods, Mild, uncomplicated allergic skin manifestations of urticaria and angio-oedema, Amelioration of allergic reactions to blood or plasma, Cold urticaria and Dermatographism.
Ciplactin is also used as a therapy for anaphylactic reactions adjunctive to Epinephrine and other standard measures after the acute manifestations have been controlled.
Ciplactin tablets are also used to stimulate the appetite and may lead to weight gain, which is helpful for underweight people who wish to gain weight.

1. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)

2. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin (Generic Cyproheptadine Hydrochloride Tablets) are
used as a therapy for Perennial and seasonal allergic rhinitis,
Vasomotor rhinitis, Allergic conjunctivitis due to inhalant
allergens and foods, Mild, uncomplicated allergic skin
manifestations of urticaria and angio-oedema, Amelioration of
allergic reactions to blood or plasma, Cold urticaria and
Dermatographism.
Ciplactin is also used as a therapy for anaphylactic reactions
adjunctive to Epinephrine and other standard measures after
the acute manifestations have been controlled.
Ciplactin tablets are also used to stimulate the appetite and
may lead to weight gain, which is helpful for underweight
people who wish to gain weight.

3. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Tablets are manufactured by Cipla Limited,
India in the strengths of 4 mg.
(Website: www.cipla.com)

4. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Cyproheptadine Hydrochloride Tablets – Brand Names
Cyproheptadine Hydrochloride Tablets
are available under various Drug trade
names that include Periactin, Peritol,
Ciplactin.

5. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Active Ingredient
The active ingredient
contained in Ciplactin
tablets is Cyproheptadine
Hydrochloride. Each
Ciplactin tablet contains 4
mg of Cyproheptadine
Hydrochloride.

6. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Chemical Structure
The structure of Cyproheptadine Hydrochloride is given
below:

7. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Uses of Ciplactin Tablets
Ciplactin (Generic Cyproheptadine Hydrochloride Tablets) is an
antihistamine used to relieve allergy symptoms such as watery eyes,
runny nose, itching eyes/nose, sneezing, hives, and itching. It works by
blocking a certain natural substance (histamine) that your body makes
during an allergic reaction. This medication also blocks another natural
substance in your body (serotonin).This medication should not be used in
newborn or premature infants.
Cyproheptadine appears to be a safe, generally well-tolerated medication
that has utility in helping facilitate weight gain in patients drawn from a
variety of underweight populations.
A significant higher body mass index was observed among
Cyproheptadine- treated patients after 8 weeks intervention with
Cyproheptadine compared with the control group.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

8. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Dosage

The dosage of Ciplactin tablets (Generic Cyproheptadine
Hydrochloride Tablets) is given below:
The dosage should be individualized according to the needs and
the response of the patient. Each tablet contains 4 mg of
Cyproheptadine Hydrochloride.
Adults: The total daily dose for adults should not exceed 0.5
mg/kg/day. The therapeutic range is 4 to 20 mg a day, with the
majority of patients requiring 12 to 16 mg a day. An occasional
patient may require as much as 32 mg a day for adequate relief.
It is suggested that dosage be initiated with 4 mg (one tablet)
three times a day and adjusted according to the size and
response of the patient.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

9. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Dosage

The dosage of Ciplactin tablets (Generic Cyproheptadine
Hydrochloride Tablets) is given below:
Paediatric Patients aged 7 to 14 years: The usual dose is 4 mg (one
tablet) two or three times a day adjusted as necessary to the size and
response of the patient. The dose is not to exceed 16 mg a day.
Paediatric Patients aged 2 to 6 years: The total daily dosage for
paediatric patients may be calculated on the basis of body weight or
body area using approximately 0.25 mg/kg/day or 8 mg per square
meter of body surface (8 mg/m2)
The usual dose is 2 mg (half tablet) two or three times a day, adjusted
as necessary to the size and response of the patient. The dose is not to
exceed 12 mg a day.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

10. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Contraindications
Ciplactin is contraindicated in patients with a hypersensitivity to
Cyproheptadine Hydrochloride, other drugs of similar chemical
structure or any other component of this medication. This medicine
should not be used in newborn or premature infants. Because of the
higher risk of antihistamines for infants generally and for newborns
and premature babies in particular, antihistamine therapy is
contraindicated in lactating mothers.
Other contraindications include Monoamine oxidase (MAO) inhibitor
therapy, Angle-closure glaucoma, Stenosing peptic ulcer,
Symptomatic prostatic hypertrophy, Bladder neck obstruction,
Pyloroduodenal obstruction, Elderly and debilitated patients.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

11. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Storage Instructions

Ciplactin (Generic Cyproheptadine
Hydrochloride Tablets) have to be stored at
controlled room temperature i.e. from 20°C to
25°C (68°F to 77°F) with excursions permitted
between 15° to 30°C (59° to 86°F).
Keep this as well as all other medicines away
from children and pets.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

12. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Warnings

Cyproheptadine Hydrochloride (Ciplactin tablets) has an
atropine-like action and, therefore, should be used with caution
in patients with the following: History of bronchial asthma,
Increased intraocular pressure, Hyperthyroidism, Cardiovascular
disease and Hypertension.
Pediatric Patients: Overdosage of antihistamines, particularly in
infants and young children, may produce hallucinations, central
nervous system depression, convulsions, respiratory and
cardiac arrest, and death.
Antihistamines may diminish mental alertness; conversely,
particularly, in the young child, they may occasionally produce
excitation.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

13. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Warnings

CNS Depressants: Antihistamines may have additive effects
with alcohol and other CNS depressants, e.g., hypnotics,
sedatives, tranquilizers, antianxiety agents.
Activities Requiring Mental Alertness: Patients should be
warned about engaging in activities requiring mental
alertness and motor coordination, such as driving a car or
operating machinery.
Antihistamines are more likely to cause dizziness, sedation, and
hypotension in elderly patients.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

14. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Tablets and Alcohol

This medicine may make you dizzy or drowsy or blur your vision.
Alcohol can increase the nervous system side effects of
Cyproheptadine such as dizziness, drowsiness, and difficulty
concentrating. Some people may also experience impairment in
thinking and judgment. You should avoid or limit the use of
alcohol while being treated with Cyproheptadine.
Do not drive, use machinery, or do anything that needs alertness
or clear vision until you can do it safely.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

15. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Side Effects
Side effects that have been reported with the use of antihistamines are as
follows:
Central Nervous System: Sedation and sleepiness (often transient),
dizziness, disturbed coordination, confusion, restlessness, excitation,
nervousness, tremor, irritability, insomnia, paraesthesias, neuritis,
convulsions, euphoria, hallucinations, hysteria, faintness.
Integumentary: Allergic manifestation of rash and oedema, excessive
perspiration, urticaria, photosensitivity.
Special Senses: Acute labyrinthitis, blurred vision, diplopia, vertigo, tinnitus.
Cardiovascular: Hypotension, palpitation, tachycardia, extrasystoles,
anaphylactic shock.
Hematologic: Haemolytic anaemia, leucopenia, agranulocytosis,
thrombocytopenia.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

16. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Side Effects
Side effects that have been reported with the use of antihistamines are
as follows:
Digestive System: Cholestasis, hepatic failure, hepatitis, hepatic
function abnormality, dryness of mouth, epigastric distress, anorexia,
nausea, vomiting, diarrhoea, constipation, jaundice.
Genitourinary: Urinary frequency, difficult urination, urinary retention,
early menses.
Respiratory: Dryness of nose and throat, thickening of bronchial
secretions, tightness of chest and wheezing, nasal stuffiness.
Miscellaneous: Fatigue, chills, headache, increased appetite/weight
gain.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

17. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Cyproheptadine Hydrochloride (Ciplactin tablets) Overdose
Antihistamine overdosage reactions may vary from
central nervous system depression to stimulation
especially in pediatric patients.
Also, atropine-like signs and symptoms (dry mouth; fixed,
dilated pupils; flushing, etc.) as well as gastrointestinal
symptoms may occur.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

18. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Cyproheptadine Hydrochloride (Ciplactin tablets) Overdose
If vomiting has not occurred spontaneously, the patient should be induced to
vomit with syrup of Ipecac.
If patient is unable to vomit, perform gastric lavage followed by activated
charcoal. Isotonic or 1/2 isotonic saline is the lavage of choice.
Precautions against aspiration must be taken especially in infants and children.
When life threatening CNS signs and symptoms are present, intravenous
physostigmine salicylate may be considered. Dosage and frequency of
administration are dependent on age, clinical response, and recurrence after
response.
Saline cathartics, as milk of magnesia, by osmosis draw water into the bowel
and, therefore, are valuable for their action in rapid dilution of bowel content.
Stimulants should not be used. Vasopressors may be used to treat hypotension.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

19. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Tablets During Pregnancy
Cyproheptadine Hydrochloride (Ciplactin tablets) has been
classified by the US FDA as Pregnancy Category B.
Reproduction studies have been performed in rabbits, mice and rats at oral or
subcutaneous doses up to 32 times the maximum recommended human oral
dose and have revealed no evidence of impaired fertility or harm to the
foetus due to cyproheptadine HCl. Cyproheptadine HCl has been shown to
be foetotoxic in rats when given by intraperitoneal injection in doses four
times the maximum recommended human oral dose.
Two studies in pregnant women, however, have not shown that
Cyproheptadine HCl increases the risk of abnormalities when administered
during the first, second and third trimesters of pregnancy. No teratogenic
effects were observed in any of the newborns. Nevertheless, because the
studies in humans cannot rule out the possibility of harm, Cyproheptadine
HCl should be used during pregnancy only if clearly needed.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

20. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Tablets During Nursing
It is not known whether Cyproheptadine Hydrochloride
(Ciplactin tablets) is excreted in human milk. Because
many drugs are excreted in human milk, and because of
the potential for serious adverse reactions in nursing
infants from Ciplactin tablets, a decision should be made
whether to discontinue nursing or to discontinue Ciplactin
tablets, taking into account the importance of the drug to
the mother.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html

21. © Clearsky Pharmacy
Ciplactin Tablets by Cipla (Generic Cyproheptadine Hydrochloride Tablets)
Ciplactin Tablets (Generic Cyproheptadine
Hydrochloride Tablets) is manufactured by Cipla
Limited, India.
URL: https://www.clearskypharmacy.biz/ciplactin-tablets-cyproheptadine-hcl.html