Co-solvents.pptx

Co-solvents

1. Co-solvents Solution: A homogenous mixture of two or more substances. Co- solvants : substances added to an immiscible solution in small amounts to increase the solubility of a poorly-soluble compound and make them mixable to each other.

2. common cosolvents for this purpose are ethanol, propylene glycol, glycerin, sorbitol and polyethylene glycol.

3. cosolvents characteristics Non-toxic Non-Irritancy V alues of Dielectric constant is in between 25-80 Specially for oral and parenteral use

4. Application Evidenced by a 2009 study in which researchers from Panjab University showed the solubility of various anti-diabetic drugs has been increased by more than 500 times by use of a cosolvent .

5. How does it work Cosolvent  system works by reducing the interfacial tension between the aqueous solution and hydrophobic solute thus making the one-phase solution.