Composite protein databases

Information on the following topics is given :-
Database; Biological database - features & needs; Types of databases and it's examples;

1. COMPOSITE PROTEIN DATABASES BY : S. DASH

2. What is a database ? A database is an organized collection of  data , generally stored and accessed electronically from a computer system. Where databases are more complex they are often developed using formal   design and modeling   techniques.

3. What is a biological database ? Biological databases are libraries of life sciences information, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis.

4. FEATURES OF A biological database:- HETEROGENEITY HIGH VOLUME DATA UNCERTAINITY DATA CURATION DATA INTEGRATION DATA SHARING DYNAMICS

5. WHY DO WE NEED BIOLOGICAL DATABASE? BIOLOGICAL DATABASES SERVE A CRITICAL PURPOSE IN THE COLLATION AND ORGANIZATION OF DATA RELATED TO BIOLOGICAL SYSTEMS. THEY PROVIDE A COMPUTATIONAL SUPPORT AND A USER-FRIENDLY INTERFACE TO A RESEARCHER FOR A MEANINGFUL ANALYSIS OF BIOLOGICAL DATA.

6. TYPES OF DATABASES:- PRIMARY DATABASES SECONDARY DATABASES

7. PRIMARY DATABASES CONTAINS BIO-MOLECULAR DATA IN IT’S ORIGINAL DATA FORM. EXPERIMENTAL RESULTS ARE SUBMITTED DIRECTLY INTO THE DATABASE BY RESEARCHERS, AND THE DATA ARE ESSENTIALLY ARCHIVAL IN NATURE. ONCE GIVEN A DATABASE ACCESSION NUMBER, THE DATA IN PRIMARY DATABASES ARE NEVER CHANGED. EXAMPLES: GenBank, EMBL and DDBJ for RNA/DNA sequences, SWISS-PROT and PIR for protein sequences and PDB for molecular structures.

8. COMPOSITE DATABASES COLLECTION OF VARIOUS PRIMARY DATABASE SEQUENCES. RENDERS SEQUENCE SEARCHING HIGHLY EFFICIENT AS IT SEARCHES MULTIPLE RESOURCES. EXAMPLES:-NDRB(Non-redundant Database), OWL,MIPSX, SWISS-PROT + Tr EMBL

9. SECONDARY DATABASES CONTAINS DATA DERIVED FROM THE RESULTS OF ANALYSING PRIMARY DATA. MANUALLY CREATED OR AUTOMATICALLY GENERATED. CONTAINS MORE RELEVANT AND USEFUL INFORMATION STRUCTURED TO SPECIFIC REQUIREMENTS. EXAMPLE:-PROSITE, PRINTS, BLOCKS, Pfam

10. REFERENCES : 1.ncbi.nlm.nih.gov/ pmc /articles/PMC308323 2.slideplayer.com 3.http://en.m.Wikipedia.org /wiki

11. THANK YOU!