Container closure system and issues facing modern drug packaging

Container closure system and issues facing modern drug packaging

1. Container Closure System, I ssues facing modern drug packaging, different Guidelines, Advantages and Disadvantages By- Sarda Prathamesh Pradeep PGDRA

2. Contents Introduction Containers Types of containers Material used for manufacture of containers Closures Purpose of closure Classification of closure Material used for manufacture of closures Issues facing modern drug packaging Advantages and disadvantages

3. Introduction Containers can be defined as an object that can be used to hold or transport something. Pharmaceutical containers is a device that can hold a pharmaceutical product and it may or may not be in direct contact with it.

4. Containers A device in which drug is enclosed and in direct contact with the drug.

5. Types of containers Well closed containers- protect the contents from loss during transport, storage Single dose containers- used to supply only one of the medicaments Multi dose containers- allow the withdrawal of dose at various intervals Light resistant containers- protect the medicaments from harmful effect of light

6. 5) Air tight containers (hermetic container)- they have air tight sealing or closing 6) Aerosol container- they have adequate mechanical strength in order to bear pressure

7. Material used for manufacture of containers Mainly four types of material used in manufacture of containers 1) Glass 2) Plastic 3) Metal 4) Rubber

8. Closures

9. Purpose of closures Retains the content Provides a barrier to dirt, oxygen, moisture, etc Keeps the product secure from undesired and premature opening Assists in dispensing and using of product Provides a totally hermetic seal

10. Classification of closures

11. Material used for manufacturing of closures Metal- aluminum, aluminum alloy Rubber- natural and synthetic Plastic- thermosetting and thermoplastic Glass

12. Issues facing modern drug packaging Globalization Regulations Economics New-product cost Speed-to-market Informed consumers Serialization and usability

13. 1) Globalization.   The push to globalize, to capitalize on huge marketplaces in rapidly developing nations with this comes pressure to adhere to complex standards. 2) Regulations.  Developing and implementing superior processes related to rapidly evolving labels and new regulatory regimens for information and anti-counterfeiting.

14. 3) Economics.  Downward price pressure due to broad governmental and economic factors is an ongoing challenge for the pharma packaging industry. 4) New-product cost.  A shrinking new-product pipeline, with fewer blockbuster drugs and increasing new-product cost.

15. 5) Speed-to-market.  The need for speed-to-market and agility to capitalize on short windows of exclusivity. 6) Informed consumers.  Consumers are paying far more attention to the health, nutritional, and fitness benefits of the brands they buy, using information they find on the internet, through social media, and on a growing selection of “clean label” products to guide their choices.

16. 7) Serialization and usability.  The requirement for a clear serialization strategy driven by the Falsified Medicines Directive — not only do patients need the correct medication without the risk of counterfeit products, they need to know how to use the packaging and have a clear understanding of how it works.

17. Advantages and disadvantages.

18. Thank you