DEFINITION Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. Symptoms include breathing difficulty, cough, mucus (sputum) production and wheezing.
Pathophysiology Due to the e t i o l o g y Inflammation Activation of n e u t r o p h i l s Inactivation of p r o t e a s e s Tisssue destruct i o n
Tissue destructi o n Chronic inflammation Hypersecretion of m u c u s Leads to chronic obstruction
Bullectomy is a procedure where doctors remove one or more of the very large bullae or blebs from the lungs. Bullae are large air sacs that form from hundreds of destroyed alveoli. These air spaces can become so large that they crowd out the better functioning lung and interfere with breathing. For those people, removing the destroyed air sacs improves breathing . Lung Volume Reduction Surgery (LVRS) is a procedure to help people with severe emphysema affecting the upper lung lobes Lung transplantation