Cosmeceuticals

for b.pharmacy students

1. welcome

2. COSMECEUTICALS SEMINAR BY Fair & lovely ( B.Pharm ) UNDER THE GUIDENCE OF K. YALLAREDDY M.pharm . JAGAN’S COLLGE OF PHARMACY NELLORE

3. CONTENTS DEFINITION APPLICATIONS CLASSIFICATION MECHANISM CHEMICAL CONSTITUENTS EXAMPLES AMLA HENNA CYPERUS SOAP NUT ALOEVERA TURMERIC SANDAL WOOD BITTER ORANGE PEEL

4. DEFINITION Cosmeceuticals are the cosmetic products which contain biologically active ingredients of plant origin having effects on users, they are the combination products of cosmetics and pharmaceuticals, intended to enhance the health and beauty of the skin.

5. DEFINITION These are differ from the cosmetics, cosmetics are the inert substances which cleanse or enhance the appearance of the skin without any therapeutic effect. Where as the pharmaceuticals are used to treat or prevent the diseases or intended to affect the physiological structure or function of the body. Pharmaceutical are scrutinized and also reviewed by FDA however one should noted that cosmetic and cosmetic ingredients are tested for safety but evidence is rarely available for the beneficial claims.

6. classification According to the region, where it is used. Skin: powders, lipstics , rouges, creams, lotions, solutions. Hair: shampoo , conditioners, creams, bleaches, colouring preparations, dyes. Nails: nail lacquers, lacquer removers Teeth: pastes, powders, gels, dentifrices Eye: eyeliners, mascaras, eye shadows, and eye brow pencils.

7. mechanism Aging of the skin is influenced by several factors such as Temperature flucuations Exposure to chemicals and gases Exposure to sunlight Exposure to pollution Uv -radiations from sunlight penetrate the skin and accelerate damage due to free radicals which includes inflammation , wrinkling, and hyper pigmentation.

8. mechanism Due to prolonged exposure of Uv -radiation the collagen and elastic fibers of the skin are broken down by the enzymes collagenase and elastase and texture of the skin is deteriorates. Collagen and elastin are responsible for maintaining the elasticity and integrity of the skin. Several plant extracts and antioxidants obtained from natural sources are able to prevent the aging and also improving the large number of cosmeceutical agents are known few of which are as retinoic acid, vitamin C and E, co-enzyme Q10, tetrahydro curcuminoids and boswellic acids .

9. examples AMLA HENNA CYPERUS SOAP NUT ALOEVERA TURMERIC SANDAL WOOD BITTER ORANGE PEEL

10. AMLA Biological source: dried and fresh fruits of “ Emblica officinalis ” family Euphorbiaceae Chemical constiyuents : Vitamin-C, tannins, pectin Uses: Amla powder and oil are used traditionally in Ayurvedic applications for the treatment of scalp. Amla powder improves immunity and gives physical strength. It improves complexion and removes wrinkles. Amla is also used to treat constipation and is used as a cooling agent to reduce the effects of sun strokes and sun burns. It is the main ingredient used in the shampoo. Amla oil is used all the world.

11. HENNA Biological sourece: it consisting of fresh and dried leaves of Lawsonia inermis belongs to family: Lythraceae . Chemical constituents: The active constituent of the leafs is lawsone , gallic acid. Lawsone is main coloring constituent is said to be a degradation product of primary glycoside Hennoside A, B and C. Uses: Henna is used as a favourite hair dye. Henna acts as a antibacterial and antifungal.

12. CYPERUS Biological source: It is obtained from the grass like leaves of the plant “ Cyperus esculentus ” family: Cyperaceae . Chemical constituents: Palmitic acids, oleic acid, linoleic acid and stearic acid. Uses: Used in cosmetic industry, antioxidant property, antiageing , favaours the elasticity of the skin, and reduces the skin wrinkles.

13. SOAP NUT Biological source: It is obtained from the friut pulp of the plant “ sapindus saponaria ” family: Sapindaceae . Chemical constituents: Saponin glycosides and tannins Uses: Natural surfactant Used in soap preparations.

14. ALOE VERA Biological source: It is the dried juice of the “Aloe barbadensis ” family: Liliaceae Chemical constituents: Anthraquinone glycosides, aloin , barbaloin , aloe emodin , chrysophanic acid,coniferyl alcohol. Uses: Used in skin cosmetics, protective and antiwrinkle property. Used in ointments, creams.

15. TURMERIC Biological source: It is the dried and fresh rhizomes of the plant “curcuma longa ” family: Zingiberaceae Chemical constituents: Curcuminoids , curcumin , volatile oils, camphene, zingiberene . Uses: Used in skin cosmetics, protective and antiwrinkle property. Used in ointments, creams, Skin Care and Colouring The skin is the main portion of the body and provides a shielding barrier against harmful chemicals, microbes, and ultraviolet radiation. Natural plant products like turmeric have been formulated to heal and prevent dry skin, treat skin conditions such as eczema and acne, and retard the aging process.

16. TURMERIC Turmeric is used in many celebrations of Hindus. Especially in Hindu wedding brides would rub with turmeric on their bodies for glowing look. New born babies also rubbed with turmeric on their forehead for good luck. Traditionally women rub turmeric on their cheeks to produce a natural golden glow, extract of turmeric has been added to creams for use as a colouring agent. Washing in turmeric improves skin complexion and also reduces hair growth on body. These constitute home remedies for skin and hair problems.

17. SANDAL WOOD Biological source: It is obtained from heart wood of “ santalum album” family: santalaceae . Chemical constituents: Terpenoids , santalol , santalone , santalene . Uses: Used in skin cosmetics, protective and antiwrinkle property. Used in ointment, creams, perfumes.

18. BITTER ORANGE PEEL Biological source: It is dried or fresh outer part of the pericarp of the ripe fruits of “ Citrus aurantium ” family Rutaceae . Chemical constituents: Volatile oil, hesperidin , vitamin-C and pectin, aurantiamarin , limonene, citral and citronellal. Uses: Used in skin cosmetics, protective and antiwrinkle property. Used in ointment, creams, perfumes.