Cpcsea guidelines for laboratory animal facility

CPCSEA guideline

1. CPCSEA Guidelines for Laboratory Animal Facility Biswash Sapkota Dept of Pharmacy MBAHS, Hetauda , Nepal

2. Introduction and Goals CPCSEA stands for Committee for the Purpose of Control and Supervision of Experiments on Animals The goal of CPCSEA is to ensure that animals are not subjected to unnecessary pains or suffering before, during or after performance of experiments on them. The animal house facility is available to promote the teaching, training and research facilities and to meet the growing demand for quality. 11-06-2021 CPCSEA Guidelines 2

3. Objectives Experiments shall be performed in every case by or under the supervision of a person duly qualified in that behalf, that is Degree or Diploma holders in veterinary science or medicine or laboratory animal science of a university. Experiments are performed with due care and humanity and that as far as possible experiments involving operations are performed under the influence of some anaesthetic of sufficient power to prevent the animals feeling pain. Animals which, in the course of experiments under the influence of anaesthetics are so injured that their recovery would involve serious suffering, are ordinarily destroyed while still insensible. Experiments on animal are avoided wherever it is possible to do so, as for example in medical schools, hospitals, colleges and the like, if other teaching devices such as books, models, films and the like, may equally suffice. 11-06-2021 CPCSEA Guidelines 3

4. Contd … Experiments on larger animals are avoided when it is possible to achieve the same results by experiments upon small laboratory animals like guinea- pigs, rabbits, mice, rats etc. As far as possible, experiments are not performed merely for the purpose of acquiring manual skill; Animals intended for the performance of experiments are properly looked after both before and after experiments. Suitable records are maintained with respect to experiments performed on animals 11-06-2021 CPCSEA Guidelines 4

5. Veterinary Care Regular basis health monitoring of the animals is carried out to ascertain the health status of pets and animals. Veterinary care is crucial to keep the animals content and healthy. Veterinarian keeps them under daily observation and monitors any behavioural changes or sign of illness for animals. He supervises their diet and sanitation and contributes to the formulation of appropriate policies and procedures for ancillary aspects of veterinary care. 11-06-2021 CPCSEA Guidelines 5

6. Animal care Laboratory houses rats, mice and rabbits. Each species of animals is housed in barrier maintained individual rooms to avoid disease transmission and inter-species conflicts. All efforts are made to maintain the animals under controlled environmental condition like temperature (22-26⁰C), relative humidity (60±10 %), 12 hrs alternate light and dark cycle with 100% fresh air exchange in animal rooms and uninterrupted power and water supply. The entire staffs ensures that every part of animal care including feeding, watering, restraining, cage cleaning, record keeping and ordering of animals, feeds, bedding materials and equipment from outside sources are monitored. 11-06-2021 CPCSEA Guidelines 6

7. Animal Ethics The animals house is registered with CPCSEA, ministry of environment and forests, Govt. of India and has an established institutional animal ethics committee(IAEC) that advises the students, teachers/ researchers on facilities, policies and practices concerning the care and use of animals accordance of CPCSEA guidelines. 11-06-2021 CPCSEA Guidelines 7

8. 11-06-2021 CPCSEA Guidelines 8 Thank you