Dr Mazen Qusaibaty MD, DIS Head Pulmonary and Internist Department Ibnalnafisse Hospital Ministry of Syrian health Email: [email protected] CT halo sign (part 2) Hampton hump sign Westermark sign
Bronchiolitis Obliterans with Organizing Pneumonia An idiopathic disease that produces polypoid granulation tissue in: Bronchioles alveolar ducts 5 ColbyTV . Pathologic aspects of bronchiolitis obliterans organizing pneumonia. Chest 1992; 102 (1 suppl ): 38S–43S.
Bronchiolitis Obliterans with Organizing Pneumonia Variable degrees of interstitial and airspace infiltration by mononuclear cells and foamy macrophages 6 ColbyTV . Pathologic aspects of bronchiolitis obliterans organizing pneumonia. Chest 1992; 102 (1 suppl ): 38S–43S.
The most common CT finding in patients with BOOP Asymmetric bilateral ground-glass opacity with a predominantly peripheral distribution (arrows) 7 Courtesy of Paul Stark, MD.
The most common CT finding in patients with BOOP 8
The most common CT finding in patients with BOOP 9
The most common CT finding in patients with BOOP 10
The most common CT finding in patients with BOOP 11
The most common CT finding in patients with BOOP 12
The most common CT finding in patients with BOOP 13
BOOP Kim et al reported that CT images of 06 of 31 patients with BOOP showed nodular ground-glass opacity 14 KimSJ , Lee KS, Ryu YH, et al. Reversed halo sign on high-resolution CT of cryptogenic organizing pneumonia: diagnostic implications. AJR Am J Roentgenol 2003; 180 : 1251–1254.
BOOP A 46-year-old woman Axial CT image at the level of the aortic arch 15 KimSJ , Lee KS, Ryu YH, et al. Reversed halo sign on high-resolution CT of cryptogenic organizing pneumonia: diagnostic implications. AJR Am J Roentgenol 2003; 180 : 1251–1254.
BOOP A 46-year-old woman Shows multiple bilateral areas of ill-defined nodular ground-glass opacity , some of which contain solid components (arrows). 16 KimSJ , Lee KS, Ryu YH, et al. Reversed halo sign on high-resolution CT of cryptogenic organizing pneumonia: diagnostic implications. AJR Am J Roentgenol 2003; 180 : 1251–1254.
Case 48-year-old woman with an eight-week history of cough , dyspnea with exertion , fatigue , and slight weight loss . 17
Case/ High-resolution CT scan of this patient RLL reticular and hazy opacities that are subpleural 18 Courtesy of Talmadge E King Jr , MD
Quiz conti………….. This picture is look like: Idiopathic pulmonary fibrosis. Sarcoidosis stage IV TB BOOP All above 19
Quiz conti………….. This picture is look like: Idiopathic pulmonary fibrosis. Sarcoidosis stage IV TB BOOP All above 20
Reverse halo sign: BOOP CT of localized organizing pneumonia manifesting as a solitary nodule of the left lower lobe 21
Reverse halo sign: BOOP This pattern may be diagnosed as primary or metastatic lung tumor 22
Thoracic Endometriosis Catamenial syndrome 23
24 AlifanoM , Trisolini R, Cancellieri A, Regnard JF. Thoracic endometriosis: current knowledge. Ann Thorac Surg 2006; 81 : 761
25 AlifanoM , Trisolini R, Cancellieri A, Regnard JF. Thoracic endometriosis: current knowledge. Ann Thorac Surg 2006; 81 : 761
26 AlifanoM , Trisolini R, Cancellieri A, Regnard JF. Thoracic endometriosis: current knowledge. Ann Thorac Surg 2006; 81 : 761
27 AlifanoM , Trisolini R, Cancellieri A, Regnard JF. Thoracic endometriosis: current knowledge. Ann Thorac Surg 2006; 81 : 761
Catamenial syndrome This disease group includes four well-recognized clinical entities Catamenial pneumothorax Catamenial hemothorax Catamenial hemoptysis Lung nodules 28 AlifanoM , Trisolini R, Cancellieri A, Regnard JF. Thoracic endometriosis: current knowledge. Ann Thorac Surg 2006; 81 : 761
CPT Catamenial pneumothorax is a rare condition characterized by a reoccurrence of air in the pleural space coinciding with the onset of menses. 29 http://www.catamenial-pneumothorax.com/id15.htm
CPT CPT was first described in literature in 1958 30 http://www.catamenial-pneumothorax.com/id2.htm
CPT It is almost always right-sided 31 http://www.catamenial-pneumothorax.com/id2.htm
CPT Generally affects women in their thirties and forties 32 http://www.catamenial-pneumothorax.com/id2.htm
CPT Although the exact etiology of the condition is unknown Most physicians agree that endometriosis is involved. 33 http://www.catamenial-pneumothorax.com/id2.htm
CPT Documented case studies have described endometrial implants on the: Lung Pleura Diaphragmatic fenestrations (holes in the diaphragm) 34 http://www.catamenial-pneumothorax.com/id2.htm
CPT Case studies report women with CPT experiencing monthly Chest pain Shortness of breath Dizziness and fatigue 35 http://www.catamenial-pneumothorax.com/id2.htm
CPT Case studies report women with CPT experiencing monthly Some women have experienced multiple lung collapses over a period of several years. Many of these women have also been diagnosed with pelvic endometriosis. 36 http://www.catamenial-pneumothorax.com/id2.htm
Case 1 In a 42-year-old woman who presented with: Three episodes of spontaneous pneumothorax , each associated with the onset of menses . 37 http://radiographics.rsna.org/content/21/1/193/F43.expansion.html
Case 1 She had undergone a prior hysterectomy for endometriosis 38 http://radiographics.rsna.org/content/21/1/193/F43.expansion.html
Case 1 Had a 2-3-year history of: Episodic cough Hemoptysis Pleuritic chest pain 39 http://radiographics.rsna.org/content/21/1/193/F43.expansion.html
Posteroanterior chest radiograph Shows a right-sided pneumothorax A nodular opacity in the right lung base (arrow) 40 http://radiographics.rsna.org/content/21/1/193/F43.expansion.html
Case 2 Chest CT scan (lung windows) Shows a 2.5-cm solitary pulmonary nodule in the right lower lobe (arrow). 41 http://radiographics.rsna.org/content/21/1/193/F43.expansion.html
Parenchymal endometrioma in a 74-year-old woman The lesion was found on a routine preoperative chest radiograph obtained for cataract surgery. 42 http://radiographics.rsna.org/content/21/1/193/F43.expansion.html
Parenchymal endometrioma in a 74-year-old woman She had been receiving estrogen replacement therapy since undergoing hysterectomy She had no known history of endometriosis 43 http://radiographics.rsna.org/content/21/1/193/F43.expansion.html
Case 3 Catamenial hemoptysis syndrome in a 24-year-old woman with recurrent monthly hemoptysis during menstruation 44 http://radiographics.rsna.org/content/27/2/391/F29.expansion.html
Axial CT image at the level of the diaphragmatic dome Multiple areas of ill-defined nodular ground-glass opacity (arrows) 45 http://radiographics.rsna.org/content/27/2/391/F29.expansion.html
The patient underwent a bronchoscopic examination, and endometrial tissue was found at bronchial lavage 46 http://radiographics.rsna.org/content/27/2/391/F29.expansion.html
Focal Traumatic Lung Injury 47
Focal Traumatic Lung Injury Traumatic lung injury may be manifested as nodular ground-glass opacity at CT during subsequent disease progression 48
Focal Traumatic Lung Injury A transthoracic lung biopsy A transbronchial biopsy 49 KazerooniEA , Cascade PN, Gross BH. Transplanted lungs: nodules following transbronchial biopsy. Radiology 1995; 194 : 209–212.
Pseudonodule in a 56-year-old woman who underwent a previous percutaneous lung biopsy Thin-section CT image obtained at the level of the aortic arch 50
Pseudonodule in a 56-year-old woman who underwent a previous percutaneous lung biopsy Shows a 9-mm well-defined nodular ground-glass opacity (arrow ) in the right upper lobe 51
Pseudonodule in a 56-year-old woman who underwent a previous percutaneous lung biopsy Axial image obtained during CT-guided percutaneous transthoracic biopsy with the patient in the supine position shows the biopsy needle (arrow), which has been inserted near the nodule 52
Pseudonodule in a 56-year-old woman who underwent a previous percutaneous lung biopsy Axial CT image, obtained after the biopsy, shows a poorly defined pseudonodule represented by ground-glass opacity (arrow) along the biopsy tract 53
Pseudonodule in a 56-year-old woman who underwent a previous percutaneous lung biopsy The pathologic diagnosis, obtained after a wedge resection, was focal interstitial fibrosis 54
Pulmonary Embolism Signs 55
Radiographic sign s with a relatively high specificity but low sensitivity for PTE Pleura-based areas of increased opacity (Hampton sign ) Decreased vascularity in the peripheral lung ( Westermarck sign ) Enlargement of the central pulmonary artery (Fleischner sign ) Hemidiaphragm elevation 56 Worsley DF, Alavi A, Aronchick JM, Chen JT, Greenspan RH, Ravin CE. Chest radiographic findings in patients with acute pulmonary embolism: observations from the PIOPED Study. Radiology 1993; 189 :
Helical CT Findings in Acute PTE 57
Helical CT Findings in Acute PTE 58
Helical CT Findings in Acute PTE 59
Helical CT Findings in Acute PTE 60
Helical CT Findings in Acute PTE 61
Helical CT Findings in Acute PTE 62
Helical CT Findings in Acute PTE 63
Acute PE
Helical CT Findings in Chronic PTE 65
Pulmonary Embolism Acute PE Central intraluminal filling defects Parenchyma: rounded pleural-based densities, pleural effusion Subacute PE Convex mural filling defects Parenchyma: oval pleural-based densities, pleural effusion Chronic PE Concave mural filling defects, intraluminal “rope ladder” Irregular wall thickening, abnormal vascular tapering, variation in size of segmental vessels Parenchyma: translobular lines, mosaic perfusion, pleural effusion BC: Wacker_Gustav_19330609_BC_zentral/Akute LE: Sauer_Erna_DOB19211226_LE CTEPH: Prell/Sarkom: Jpn. J. Clin. Oncol. Uchida et al. 35 (7): 417
Chronic PE Concave mural filling defects 67
Chronic PE Intraluminal “rope ladder” 68
Hampton hump sign 69
Hampton hump sign A homogeneous wedge-shaped consolidation in the lung periphery
Hampton hump sign A base contiguous to a visceral pleural
Hampton hump sign A rounded convex apex directed toward the hilum
Hampton hump sign Associated with pulmonary infarct
Hampton hump sign Left intraluminal filling defects in left pulmonary artery Pulmonary infarction secondary to pulmonary embolism Bilateral pleural effusion 74
Computed tomography angiogram in a 53-year-old man with acute pulmonary embolism This image shows an intraluminal filling defect that occludes : The anterior basal segmental artery of the right lower lobe Acute Pulmonary Embolism (Helical CT): Imaging Contributor Information and Disclosures Updated: May Author: Kavita Garg , MD, Professor, Department of Radiology, University of Colorado Health Sciences Center- 14, 2008
Computed tomography angiogram in a 53-year-old man with acute pulmonary embolism An infraction of the corresponding lung, which is indicated by: A triangular, pleura-based consolidation (Hampton hump) Acute Pulmonary Embolism (Helical CT): Imaging Contributor Information and Disclosures Updated: May Author: Kavita Garg , MD, Professor, Department of Radiology, University of Colorado Health Sciences Center- 14, 2008
Case 3 A young man who experienced: Acute chest pain Shortness of breath after a transcontinental flight 77 Acute Pulmonary Embolism (Helical CT): Imaging Contributor Information and Disclosures Updated: May Author: Kavita Garg , MD, Professor, Department of Radiology, University of Colorado Health Sciences Center- 14, 2008
Case 3 Computed tomography angiography This image demonstrates a clot in : The anterior segmental artery in the left upper lung A clot in the anterior segmental artery in the right upper lung 78 Acute Pulmonary Embolism (Helical CT): Imaging Contributor Information and Disclosures Updated: May Author: Kavita Garg , MD, Professor, Department of Radiology, University of Colorado Health Sciences Center- 14, 2008
Westermark sign 79
Westermark sign Refers to an area of oligemia with minimal change in lung volume distal to a large PE
Westermark sign This regional oligemia is caused either by: Mechanical obstruction to blood flow by the clot Reflex vasoconstriction
Case 4 A 41-year-old woman presented to the emergency department complaining of a three-day history of left-sided chest pain . 82
Case 4 The pain was described as pressure-like, pleuritic, made worse with ambulation and when supine. 83
Case 4 The pain was constant, increasing in intensity and not associated with any alleviating factors, hence her request for evaluation 84
Case 4 Six weeks prior to the onset of her chest pain she had complained of: Right hip pain, radiating down the leg. This was diagnosed as radicular pain secondary to sciatica for which she had been under bed rest and analgesics 85
Case 4 Her past medical history was remarkable for: Depression Occasional migraine headaches Two cesarean sections Oral contraceptive 86
Case Physical examination was normal 87
Axial CT image of the chest A mass extending outside the vessel wall + a large filling defect involving the left main pulmonary artery and extending into all sub-branches. 88
Coronal reformatted CT image of the chest Demonstrating a mass extending outside the vessel wall 89
Sagittal reformatted CT image of the chest Demonstrating a mass extending outside the vessel wall 90
What diagnosis that do you expect? Left large cell carcinoma Bronchioloalveolar carcinoma Left small cell carcinoma Chronic left chronic pulmonary embolism Pulmonary angiosarcoma 91
What diagnosis that do you expect? Left large cell carcinoma Bronchioloalveolar carcinoma Left small cell carcinoma Chronic left chronic pulmonary embolism Pulmonary angiosarcoma 92