cytochrome

overview of cytochrome and its function

1. Cytochrome Feroze Hussain (8828) Presented by DEPARTMENT OF CHEMISTRY CENTRAL UNIVERSITY OF HARYANA 1 M.Sc. 3 rd semester 1 12-Oct-17

2. Content Introduction Types Cytochrome C Role of Cytochrome Conclusions References Acknowledgement 2 12-Oct-17

3. Cytochrome Color Protein Heme group Transfer electron 3 12-Oct-17

4. Heme group 4 12-Oct-17

5. Heme group 5 12-Oct-17

6. Heme types 6 12-Oct-17

7. Cytochrome types A B C 7 12-Oct-17

8. Cytochrome C Heme - protein attached with inner- mitochondrial membrane Higly water soluble Redox Electron transfer in Complexes 8 12-Oct-17

9. Distribution In animals, plants, and unicellular organisms In Plants – ETC In animals – ETC Evolutionary Biology 9 12-Oct-17

10. Structure Heme group has polypeptide chain wrapped around it Contains Variable number of Amino acids Nitrogen atom from histidine and a Sulfur atom from methionine segment are coordinated with Iron atom 10 12-Oct-17

11. Cytochrome -C- Oxidase Uses metal to shuffle electron into oxygen molecule 4 Fe 2+ -cytochrome  c  + 8 H + in  + O 2  → 4 Fe 3+ -cytochrome  c  + 2 H 2 O + 4 H + out 11 12-Oct-17

12. Power House Of The Cell Semi- autonomous cell Organelle. Electron Transport Chain 12 12-Oct-17

13. Electron Transport Chain 13 12-Oct-17

14. Complex 3 rd Also called cyt bc1 complex Has cyt B and Cyt C Cyt B has Heme B Cyt c has Heme C Reskie iron sulfur also present 14 12-Oct-17

15. Complex 4 th Also known as cyt a complex Has various subunits Subunit 1: heme groups and Cu ion Subunit 2: Has 2 Cu ion Subunit 3: role not clear but important for the functioning of this complex 15 12-Oct-17

16. Conclusions 16 12-Oct-17 Electron transferring protein Cytochrome types differ by attachment of different groups C ytochrome found in all sort of life Mitochondria in which cytochrome plays its role Electron transport chain complexes involves in the ETC ATP

17. References Inorganic chemistry ; James E. Hueey , 663-666. GOOGLE Principles of Biochemistry ; David L.Nelson 17 12-Oct-17

18. Acknowledgement Dr. Prakash Kanoo Dr. Manoj Kumar Gupta 18 12-Oct-17

19. 19 12-Oct-17