A nucleotide consists of: 1._____________ 2. ____________ 3._____________ Bell warm up 01/07/10
Importance of DNA Genetically engineered glowing tobacco plant Genetically engineered glowing fish
DNA Replication
DNA Notes DNA = Deoxyribo nucleic acid Made up of repeating units called nucleotides. A nucleotide consist of ( sugar (deoxyribose), phosphates and nitrogeneous bases
Base pairing Rosalind Franklin’s DNA image “Chargoff’s rule” A = T & C = G
Cell division and DNA replication Cells divide Growth, Repair, Replacement Before cells divide they have to double cell structures, organelles and their genetic information
Notes: Structure was discovered in 1953 by James Watson and Francis Crick
DNA replication
DNA replication DNA Replication Steps 1. DNA unwinding 2. Unzipping (hydrogen bonds break) 3. New strands made– free floating nucleotides form to build new strand Note: DNA replication is said to be Semi-conservative because: One strand is the original (conserved) One strand is freshly assembled (semi-half)
DNA replication steps unzipping New nucleotides assembled DNA
DNA replication http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/dna-rna2.swf
DNA replication Let’s build our own DNA model and simulate DNA replication. http://www.phschool.com/atschool/phbio/dna_replication/index.html
DNA replication DNA Double helix game http://nobelprize.org/educational_games/medicine/dna_double_helix/
Replication Lab Pick A T C G C T (lay them on the table) Make the other side to make a double helix Now lets replicate: 3. UNWIND your DNA get teacher’s approval 4. UNZIP your DNA Build new strands Put the labels in the correct places ( DNA polymerase, new strand, old strand )
Lab 2 Create your own DNA with 6 rungs or steps REPLICATE Show your teacher the end product with the lables in the correct places Complete the given worksheet Turn in your work as a group , clean up and go back to your seat in front