Drugs in obstetrics

Detailed description of drugs in obstetrics for the midwifery students and beginners. Easy reference in one powerpoint presentation. Key details of drugs are mentioned . All drugs discussed as per INC Nursing syllabus for BSc & MSc Students.

1. Drugs in Obstetrics By: Maj Saminder Malik

2. Drugs in Obstetrics

3. Oxytocic in Obstetrics

4. Oxytocin

5. Oxytocin (preparations)

6. Indications

7. Contraindications

8. Adverse effects

9. Nurse’s responsibilities

10. Nurse’s responsibilities

11. Ergot derivatives Preparation Ampoules Tablet Ergometrine ( ergonovine ) 0.25mg or 0.5mg 0.5mg Methergine ( methylergonovine ) 0.2mg 0.5-1mg Syntometrine (Sandoz) 0.5mg ergometrine 0.5-1mg +5 U syntometrine

12. Onset of action Routes Ergometrine methergine IV 45-60sec 5min IM 6-7min 7min Oral 10min 10min

13. Mode of action

14. Indications

15. Contraindications

16. Ergot derivatives

17. Ergot derivatives

18. Prostaglandins

19. Prostaglandins Routes Availability Preparation Dose Vaginal route Dinoprostone ( prostin E2) Vaginal tablet 3mg in post. Fornix. Repeat dose after 6-8 hrs. Max dose 6mg Releasing dinoprostone Vaginal pessary 10mg over 24hrs. Removed when cervix is ripe Prostin E2 ( cerviprime ) Vaginal gel 0.5mg at/below internal os Parenteral PGE2 IV 1mg/ml PGF2a ( dinoprost tromethamine ) IM 5mg/ml Methyl analogue of PGF2a ( carboprost ) IM 250mcg/ml Methyl ester of PGE1 ( misoprost ) tablets

20. Contraindications

21. Side effects

22. Prostaglandins - uses

23. Nurses' responsibility

24. Epidosin ( valethamate bromide)

25. I ndications

26. Route of administration & dose

27. Anti-hypertensive therapy Sympathomimetics Adrenergic receptor blocking agent Vasodilators Calcium channel blockers Methyldopa Labetalol Hydralazine Nifedipine

28. Methyldopa

29. Methyldopa

30. Labetalol

31. H ydralazine

32. Nifedipine

33. Tocolytic agents

34. Betamimetics

35. Betamimetics

36. Betamimetics

37. PG synthetase inhibitor - Indomethacine

38. Calcium Channel blockers

39. Magnesium Sulphate

40. Oxytocin antagonists - Atosibvan

41. Anticonvulsants – MgSo4

42. MgSo4 – Toxic levels

43. MgSo4 - side effects

44. Diazepam

45. Analgesia & anesthesia in obstetrics

46. Pethidine

47. Fentanyl

48. P entazocin

49. Tranquilizers

50. Inhalational methods

51. Epidural and spinal regional analgesia

52. Pudendal block

53. Epidural anaesthesia

54. Spinal block

55. Para-cervical block

56. General Anesthesia