Enzyme (definition , properties and function of enzyme

This is a short slide for understanding the definition , properties and function of enzyme

1. Welcome Ladies And Gentlemen

2. Enzymes *Definition *Properties *Function

3. Catalyst Substance that increase the velocity of a reaction. Do not undergo any change.

4. Enzyme Soluble colloid organic catalyst Protein in nature except some RNA catalytic enzymes Accelerate the reaction Have the specificity

5. According to Summer and Myrback – Enzymes are simple or combined proteins acting as specific catalyst

6. Properties Protein in nature (except some catalytic RNA enzymes ) Fast a reaction 10 7 times more High specificity Act in optimum at pH(4-5) and temperature at (35-40°C)

7. Sometimes needs inorganic and organic compounds for action Have a life of several weeks or month then get broken down or replaced by new

8. Do not alter the equibrillium

9. Function Used for various purposes Ex- Renin for cheese making - Papain for meet cooking - Penicillin synthetase for penicillin production

10. Used for disease diagnosis Ex-* AST( Aspertate Aminotransferase ) /SGOT(Serum glutamic oxaloacetic transaminase ) Liver disease Myocardial infarction

11. *ALT( Alanine Aminotransferase )/SGPT(serum glutamic pyruvic transaminase ) Liver disease Kidney disease

12. *Lipase increased Pancreatic tumor Stomach & cholecystitis problems

13. *Alkaline phosphatase increased

14. *Acetylcholine esterase increased Nephrotic syndrome *Lactate dehydrogenase increased Tissue damage and organ failure * Creatine kinase increased Heart attack Muscle injury Strenuous exercise Drinking too much alcohol Taking certain medicine and supplement

15. Treatment of certain diseases Ex- *Streptokinase Myocardial infarction Pulmonary embolism Arterial thromboembolism * Urokinase (clot busting ) Blood clot in the lung