Erwin chargaff

8,435 views 6 slides Mar 01, 2012
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Erwin Chargaff Project- Garrett Vaughn and Christian Skinner


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Erwin Chargaff Garrett Vaughn Christian Skinner

Biography Erwin Chargaff was born on August 11, 1905 and died while living in New York on June 20 2002. He was an Austrian biochemist who immigrated to the United States during the Nazi era, and was a Professor of biochemistry at Columbia University medical school. Chargaff had one son, Thomas, with his wife Vera Broido, who he married in 1928. Chargaff became an American citizen in 1940 after being born in what is now the Ukraine.

Chargaff’s Rules Through careful experimentation, Chargaff discovered two rules that helped lead to the discovery of the double helix structure of DNA. The first and best known achievement was to show that in natural DNA the number of guanine units equals the number of cytosine units and the number of adenine units equals the number of thymine units. The second of Chargaff's rules is that the composition of DNA varies from one species to another, in particular in the relative amounts of A, G, T, and C bases.

Experiments He Used He was the first to find the equation for different bases To find this, he used paper chromatography which separated the purines and the pyrmadines and ultraviolet light absorption which determines how much of a base is in DNA by seeing how much light each absorbs.

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Bibliography Http://angelfire.com/ks3/deoxyribonucleicacid/history.html Http://www.bookrags.com/biography/erwin-chargaff/
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