FDA’s notification on S.W.A.G (Sex With A Grudge)

On 16th Apr 2014, The Food and Drug Administration (FDA) is advising consumers not to purchase or use S.W.A.G (Sex With A Grudge).

1. FDA’s Notification on S.W.A.G Dr. P.Naina Mohamed Pharmacologist

2. Introduction On 16 th Apr 2014, The Food and Drug Administration (FDA) is advising consumers not to purchase or use S.W.A.G (Sex With A Grudge). S.W.A.G is promoted and sold for sexual enhancement on various websites, including www.SexWithAGrudge.com , and in some retail stores.   FDA laboratory analysis confirmed that S.W.A.G contains Sildenafil. Sildenafil is a Phosphodiesterase 5 (PDE 5 ) inhibitor, useful for the treatment of Erectile Dysfunction (ED).

3. Possible Mechanism of Action

4. Interaction with Nitrates

5. Interaction with Protease Inhibitors ( Antiretrovirals )

6. Interaction with CYP3A4 Inhbitors

7. Conclusion FDA warns the Consumers should stop using this product immediately and throw it away.  FDA advises the Consumers who have experienced any negative side effects should consult a health care professional as soon as possible.  FDA announces to the public of a growing trend of dietary supplements or conventional foods with hidden drugs and chemicals.  These products are typically promoted for sexual enhancement, weight loss, and body building, and are often represented as being “all natural.”  FDA claims that they are unable to test and identify all products marketed as dietary supplements on the market that have potentially harmful hidden ingredients.  FDA advises the Consumers to exercise caution before purchasing any product in the above categories.

8. References http:// www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/MedicationHealthFraud/ucm393557.htm?source=govdelivery&utm_medium=email&utm_source=govdelivery http:// www.micromedexsolutions.com Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e Laurence L. Brunton , Bruce A. Chabner , Björn C. Knollmann Harrison's Online Featuring the complete contents of Harrison's Principles of Internal Medicine, 18e Dan L. Longo, Anthony S. Fauci , Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo , Eds. Hurst's The Heart, 13e Valentin Fuster , Richard A. Walsh, Robert A. Harrington Basic & Clinical Pharmacology, 12e Bertram G. Katzung , Susan B. Masters, Anthony J. Trevor Clinician's Pocket Reference, 11e Leonard G. Gomella , Steven A. Haist

9. References http://www.nlm.nih.gov/medlineplus/druginfo/meds/a699015.html http://www.rxlist.com/viagra-drug/clinical-pharmacology.htm http://www.medicinenet.com/sildenafil/article.htm http:// www.pfizer.com/files/products/uspi_viagra.pdf