Genetically modified cattle treating Ebola.ppt

Genetically modified cattle treating Ebola

1. 9.1 Manipulating DNA

2. 9.1 Manipulating DNA
•Transgenic animals are used to study diseases and
gene functions.
–transgenic mice used to study development and
disease
–gene knockout mice used to study gene function

3. 9.1 Manipulating DNA
Genetically modified cattle treating Ebola???
•Using cloned, genetically engineered cattle –identical, part
human
•Incubating antibodies against ebola –will be in blood plasma
•Genetically engineered to produce human antibodies
INSTEAD of cattle antibodies
•Vaccinated against deadly disease to make them produce
antibodies which can then be removed and used to treat
humans
•Similar to transfusing patients with survivor serum
•30-60L of plasma enough = 500-1,000 doses/month/animal
•Currently being used on mice –can protect if only exposed
one day with one dose, beyond that working on everyday
doses
•Next monkeys and then onto humans
•Hantavirus, flu, MERS as well –50 cattle currently