DVM, VAS, HSTU, Dinajpur-5200 Dept. of Medicine, Surgery and Obstetrics HSTU, Dinajpur-5200 an assignment on gid disease Course title: Clinics Surgery Course code: MSO-514
Introduction Gid disease is the disease caused by the invasion of the brain and spinal cord by coenurus cerebralis which is the intermediate stage of the tapeworm taenia multiceps , which inhibits the intestine of dogs and wild canidae . The syndrome produced is one of the localized, space occupying lesions of the CNS.
Etiology Caused by the larval stage of T. multiceps from the genus Taenia . The adult worms are whitish, dorso -ventrally flattened and segmented The larval stage is developed into a round to oval shaped cyst which is a white translucent structures, filled with fluid and protoscolices attached to inner surface of the cyst.
Epidemiology Distribution: world wide Occurrence: 72% infection occurred when the animals are between 6-24 months of old. Susceptible age: young lamb/kids aged 6-8 weeks are highly susceptible
transmission and pathogenesis The transmission of infection by T. multiceps take place between the dogs (definitive host) and the domestic herbivores (intermediate host) The dogs get infected when they ingest animals infected with T. multiceps . The eggs are expelled into the feces of infected dogs which acts as the source of infection The eggs are ingested by the herbivores during grazing and infect them. The onchospores come out from the intestine and localize into the brain through blood circulation where the ochospores form cyst.
Clinical findings Circling movement based on the site of cyst Blindness Head raising Anorexia and salivation Softness of skull bone found at advanced stage Skin become wrinkled over softer bone
Diagnosis Diagnosis can be made based on, History: of regular deworming or last anthelmintic treatment Clinical signs: the characteristic clinical signs of circling movement Diagnosis by radiography
Differential diagnosis Polioencephalitis Hydatidiosis Tumors and Abscess of brain
Treatment There is no effective medicinal treatment for this condition. The only way of treating it is surgery. Surgical anatomy: Blood supply: cornual artery and part of auricular artery Nerve supply: branches of cornual nerves. Site of operation: 1 cm behind the respective horn or around 1-1.2 cm left to the midline plane
Anesthesia: about 4-5ml 2% lignocaine HCl ( jasocaine ) should be infiltrated by SC injection Surgical procedure: The operative site should be clipped, shaved and washed with tincture of iodine Place the animals on lateral recumbency . A cross' incision of 2.5-3 cm diameter is made right down the bone and the edges are hold out with artery forceps to open the site. Then a small incision is made over the bone just to hold the periosteum with the rat tooth forceps. The bone should be broken with rat tooth forceps (sometimes trephining may be necessary).
5. The meninges may need to incise with handle and blade very carefully. The brain tissue is to be damaged little by little to bring out the cyst, the superficial cyst may come out immediately.In case of little bit deep seated cyst the probe should be introduced and careful circling movement of the probe is essential for releasing the cyst from brain tissue, If cysts is more deep seated, keep moving the probe and damage more brain tissue for successful operation, however, haemorrhage must be encountered. 6. When cyst is appeared allow the animal to move its head, hold the cyst with dry cotton and try to pull out the cyst 7. After delivery of the cyst, extra fluid in the brain should be removed Surgical procedure ( Cont …)
8. Sulphanilamide powder may be used before suturing the wound with nylon thread. 9. A benzoin seal is necessary and oil of turpentine should be used around the wound. 10. If bleeding is more 5% dextrose-saline about 500 ml should be infused intravenously... Surgical procedure ( Cont …)
Post-operative care and management Antibiotics should be given like streptopenicillin (inj. Streptopen-2.5g, @ 1ml/10kg body weight) Anti-inflammatory drugs should be given like meloxicam @ 0.5mg/kg, single dose Fluid therapy up to oral feeding like DNS-5% @ 500ml/day. Advice to keep the animal in clean house and not allowed to rub its head against any objects. Stiches should be removed after 8-10 days