GIT disorders Pharmacognosy Advanced.pptx

Pharm D

1. HERBAL DRUGS USED FOR GIT DISORDERS

2. TABLE OF CONTENT: 2 Herbal drugs for GIT Disorders: 1: Foeniculum Vulgare 2: Ferula foetida 3: Cuminum cyminum 4: Aegle marmelos 5: Prunus domestica

3. GESTROINTESTINAL TRACT DISORDERS 3

4. GIT disorders, Foeniculum vulgare 4

5. Functions of GIT:- 5

6. 6 Signs Of GIT Disorders

7. THANK YOU! Foeniculum vulgare MEDICINAL PLANTS FOR GIT DISORDERS Biren Shah, Avinash Seth-Textbook of Pharmacognosy pg no. 299-301

8. 8 Synonyms : Common Fennel, Large Fennel, Sweet Fennel, Wild Fennel. BIOLOGICAL SOURCE Foeniculum vulgare Miller., belonging to family Umbelliferae . FENNEL

9. 9 Nutrients in Fennel : vitamin, fiber, potassium, folate, copper, iron, magnesium Chemical constituents: anethole phenolic ester ketone Fenchone Foeniculum vulgare

10. 10 Helps in the proper disintegration of food in the body. Also helps in absorbing the nutrients and also decreases inflammation in stomach and intestines. Helps in reducing bloating and flatulence. Aspartic acid has carminative properties. It also has laxative properties USES:- Some of various uses of foeniculum vulgare are mentioned below:

11. Ferula foetida & Cuminum cyminum 11

12. Ferula foetida : 12 Synonyms : Devil’s dung; food of the gods; asafoda ; asant ; hing (Hindi). B.O : Ferula asafoetida L, F. foetida , Royel , F. rubricaulis Boiss , and some other species of Ferula, family Apiaceae .

13. 13 Part used : Dried latex exuded from the rhizome or tap root . . Ferula foetida

14. 14 Resins (40-65%) (pinene, vallinine , ferullic acid) Gums( 25%) Volatile oil (4-20%) ( ledenoxid , isoledene, gurjenene , pinene e.t.c ) Umbelliferone Disulphides and trisulphides Foetidin , phellandrene Isobutyl propanyl disulphide (C6 H16S2 ) Ferula foetida Chemical constituents

15. 15 Structures: Ferulic acid Umbellic acid Umbelliferon

16. 16 BENEFITS TO RESPIRATORY SYSTEM : Treat chest congestion , whooping cough, bronchitis , asthma Ancient folk remedy to treat cold in children Greater potency against Influenza A virus. BENEFITS TO REPRODUCTIVE SYSTEM : Cure impotency, spermatorrhea Treats dysmenorrhea, irregular cycle, anxiety, fatigue, other problems related to mensus . Contraceptive also increase the quality and quantity of breast milk so good in post pregnancy. Uses /Clinical Significance

17. 17 BENEFITS TO ORAL HEALTH : Aids in treating toothaches , bleeding gums , bad breath and harmful cavities. BENEFITS TO ENTIRE SYSTEM : Increase insluin level by stimulating the pancreatic cells Curbs the growth of malignant cells TAMASIC in Ayurveda balance hyperactive , chaotic system Used as pesticides and insecticides Uses conti …

18. 18 Treats flatulence , colic and indigestion as it decreases the growth of indigenous micro flora in gut Cleans intestinal flora and augments digestive fire Relieves cramps and increase appetite Treat abdominal injuries since 18 th century . Antispasmodic effect Anti- helmintic effect Anti- ulcerogenic effect REF:biren shahbook pg 319,320,321 GIT Uses of Ferula foetida

19. Cuminum cyminum Botanical name : Cuminum cyminum Definition : Dried ripe fruits of Cuminum cyminum Linn., family Umbelliferae . Common name : cumin, zeera Part used : Fruits Distribution : It is grown in Iran, India, Pakistan, Morocco, China 19

20. 20 Proteins volatile oils (2.5-4%) Cuminaldehyde (main volatile oil) α- pinene , β- pinene Hydrated cuminaldehyde Cruminic alcohol Hydro- cuminine Cuminum cyminum CHEMCAL CONSTITUENTS : Cuminaldehyde (Bioactive compound )

21. 21 Antioxidant Antimicrobial Anticarcinogenic Antidiabetic Helps to treat diarrhea Cuts Fat. Balance and Re-hydration Rich in fiber  Fights Anxiety Cumin seeds are used in cooking. Cuminum cyminum PHARMACOLOGICAL USES

22. 22 Taken before meals as an appetizer. Aids in digestion . For acidity , hyperacidity, stomach burning,  anorexia and gaseous distension. For constipation, worm infestation, and fever  Relieving dyspeptic symptoms. Contains antispasmodic effects. Antiulcerogenic effect.  Cuminum cyminum Uses in GIT

23. 23 BIRENSHAH BOOK ASAFOETIDA (PG319,320,321) CUMIN (PG 303,304 ) REFERENCE

24. Aegle marmelos & Prunus domestica 24

25. Aegle Marmelos : 25 Bael fruits, Bel, Indian Bael , Bengal Quince, Belan . Biren Shah, Avinash Seth-Textbook of Pharmacognosy pg no. 172-174

26. 26 Synonyms: Bael fruits, Bel, Indian Bael , Bengal Quince, Belan . Biological Source: Aegle marmelos Corr., belonging to family Rutaceae . Aegle Marmelos :

27. 27 Chemical Constituents: The chief constituent of the drug is marmelosin A, B and C, which is a furocoumarin . Other coumarins are marmesin , psoralin and umbelliferone . The drug also contains carbohydrates, protein, volatile oil and tannins. The pulp also contains good amount of vitamins C and A. Two alkaloids O- methylhalfordinol and isopentylhalfordinol have been isolated from fruits. Other alkaloids reported in the drug are angelenine , marmeline and dictamine . Aegle Marmelos :

28. 28 Structures:

29. 29 Uses: Drug is very popular in Ayurveda and is used in diarrhoea and dysentery. Action is attributed to mucilage. Leaves contain alkaloids and are considered useful in diabetes. The oil obtained from seeds possesses antibacterial, antiprotozoal and antifungal properties. The root of bael is one of the constituents of well-known Ayurvedic preparation Dasmula . In large doses it may lead to abortion, therefore, it can be used as abortifacient agent and hence it should not be used in pregnant women. Aegle Marmelos :

30. Prunus Domestica : 30 Plum tree

31. 31 Synonyms: Plum tree Biological Source: Dried fruits of Prunus domestica belonging to family Rosaceae . Prunus Domestica :

32. 32 Chemical contituents : The ripe fruit contains sugar, gum, albumen, malic acid, pectin, vegetable fibre , etc. Seeds yield volatile oil; α- pinene , β- pinene , β- caryophyllene . Flavonoids, flavonoid glycosides, abscisic acid, lignans , carotenoid pigments and carbohydrates. Prunus Domestica :

33. 33 Structures: Abscisic Acid

34. 34 USES: Super-food known for cancer prevention, digestive health, brain health, blood sugar and weight loss. Due to dietary fibre i.e good for smooth functioning of digestive system and cure constipation; natural laxative. It is good in the metabolism of carbohydrate, protein and fat.  Iron is good in the formation of RBC. Potassium helps to regulate heart beat and blood pressure. Fluoride is beneficial for strengthening of teeth. Prunus Domestica :

35. 35 USES: Vitamin C helps fight infections. Beta carotene good for eyesight and skin. Helps to reduced cholesterol. Used in treatment of diabetes. used for strengthening of teeth. used as febrifuge. Prunus Domestica :

36. 36 USES in GIT Disorders: Prunus Domestica :

37. Thank You 37