HAEMATINIC AGENT-1.pptx

its all about were description given helmatinic drugs

1. APOLLO COLLAGE OF PHARMACY ANJORA PHARMACOLOGY GUIDED BY MR. HARI PRASAD SONWANI PRESENTED BY DUSHYANT KUMAR JAYPRAKASH SAHU NITIN DESHMUKH UDAY SATNAMI

2. HAEMATINIC AGENT

3. s HAEMATINICS HAEMATINICS ARE COMPOUNDS REQUIRED IN THE FORMATION OF BLOOD AND ARE USED TO THE TREATMENT OF ANAEMIAS. HAEMATINICS INCLUDE: IRON. VITAMIN B12. FOLIC ACID.

4. CLASSIFICATION HEAMATINICS IRON MATURATION FACTORS ADJUVANT HAEMATINICS ORAL IRON PARENTERAL IRON Ferrous sulfate Ferrous fumarate Ferrous gluconate Ferrous succinate Ferrous aminoate Ferric ammonium Citrate Ferric hydroxy Polymaltose Carbonyl iron Iron- cal.complex Iron-dextran Iron-sorbitol-citric acid Ferrous sucrose Ferric carboxy- maltose Vitamin B12 Cyanocobalamin Hydroxocobalamin Methyl cobalamin Folic acid: Folinic acid (leucovorin, Citrovorum factor) Copper Pyridoxine Riboflavin

5. IRON IRON IS ESSENTIAL FOR HEMOGLOBIN PRODUCTION .TOTAL BODY IRONS ABOUT 2.5 TO 5 GRAMS, TWO-THIRD OF WHICH IS PRESENT IN HEMOGLOBIN . EACH MOLECULES OF HEMOGLOBIN HAS 4 IRON CONTAINING RESIDUES. ALSO PRESENT IN MYOGLOBIN , THE CYTOCHROMES AND OTHER ENZYMES.

6. DAILY REQUIREMENTS OF IRON ADULT MALE. - 0.5-1 MG ADULT FEMALE - 1-2 MG PREGNANCY AND LACTATION - 3-5 MG

7. DIETARY SOURCES OF IRON FOOD ITEMS THAT ARE RICH IN IRON ARE : LIVER EGG YOLK MEAT FISH , CHICKEN SPINACH DRY FRUIT WHEAT AND APPLE

8. FUNCTIONS OF IRON PRIMARY COMPONENT IN RED BLOOD CELLS CELL GROWTH AND DIVISION OXYGEN TRANSPORT DNA SYNTHESIS

9. DEFICIENCY IRON DEFICIENCY ANAMEIA BLOOD LOSS LACK OF RED BLOOD CELLS PRODUCTION HIGH RATE OF RED BLOOD CELLS DISTRUCTIONS

10. DRUGS NAME ORAL – ZINCOFER – XT IV – IRON SUCROSE

11. USE OF IRON IRON DEFICIENCY ANAEMIA IRON IS GIVEN IN CONDITION WITH INCREASED IRON REQUIREMENT AS IN PREGNANCY

12. VITAMIN B12 VITAMIN B12 (CYNOCOBALAMIN) IS SYNTHESIZED BY MICROORGENISM. THE DIETARY SOURCES OF B12 ARE : FISH EGG YOLK MEAT CHEESE VIT B12 OCCURS AS WATER SOLUBLE,THERMOSTABLE RED CRYSTALS.

13. DAILY REQUIREMENT PREGNANCY – 1-3 MG LACTATION – 3-5 MG

14. FUNCTIONSOF VITAMIN B12 MAINTAIN HEALTHY NERVES CELLS HELPS IN THE PRODUCTION OF DNA RNA HELP MAKE RED BLOOD CELLS

15. DEFICIENCY VITAMIN B12 DEFICIENCY MAY BE DUE TO ADDISONIAN PERNICIOUS ANAEMIA GASTRECTOMY CHRONIC GASTRITIS

16. DRUGS NAME ORAL – NEROBION FORTE NUROKIND IV - NUROKIND PLUS RENERVE PLUS

17. USE VITAMIN B12 DEFECIENCY TREATMENT OF MEGALOBLASTIC ANAEMIADUE TO B12 DEFICIENCY PERNICIOUS ANAEMIA NEUROPATHIES: NEUROPATHIES THROUGHT TO BE DUE TO B12 DEFICENCY LIKE TROPICAL NEUROPATHY RESPOND TO VITAMIN B12 BUT THE MECHANISM IS NOT CLEAR.

18. FOLIC ACID FOLIC ACID IS PTEROYLGLUTAMIC ACID. IT WAS FIRST ISOLATED FROM SPINACH AND, THEREFORE, NAME AS FOLIC ACID

19. DIETARY SOURCE GREEN VEGETABLES LIVER YEAST MILK SOME FRUITS

20. DAILY REQUIREMENT AN ADULT IS <0.1 MG BUT DIETARY ALLOWANCE OF 0.2 MG/DAY IS RECOMMENDED DURING PREGNANCY,LACTATION OR ANY CONDITION OF HIGH METABOLIC ACTIVITY, 0.8 MG/DAY IS CONSIDERED APPROPRIATE

21. FUNCTIONS OF FOLIC ACID SYNTHESIS OF DNA NORMAL MATURATION OF RBC AND WBC SYNTHESIS OF PURINE AND PYRIMIDINE

22. DEFICINCY FOLATE DEFICIENCY CLINICAL MANIFESTATION MEGALOBLASTIC ANAEMIA GLOSSITISS DIARRHOEA AND WEAKNESS

23. DRUGS NAME ORAL – FOLVITE FERORIL-XT

24. USES MEGALOBLASTIC ANAEMIA PREGNANCY LACTATION INFANCY

25. REFERENCE TRIPATHI, K.D.(2018). ESSENTIALS OF MEDICAL PHARMECOLOGY (8 TH ED.).JAYPEE BROTHERS MEDICAL MEDICAL PHARMECOLOGY PADMAJA UDAYKUMAR PUBLISHERS: CBS PUBLISHERS & DISTRIBUTERS ,NEW DELHI, FOURTH EDITION 2013 KAEWN, W. (2015)LIPPINCOTT ILLUSTRATED REVIEWS PHARMECOLOGY. 6 TH EDITION, EOLTERS KLUWER, ALPHEN AAN DEN RIJN, 456-457. TARA V SHANBHAG & SMITA SHENOY ; PHARMECOLOGY FOR MEDICAL GRADUATES, 5 TH EDITION ; ELSEVIER.

26. THANK YOU