Heck reaction

HECK COUPLING REACTION

1. Introduction to Heck Reaction Presented By:- Harbansh Singla Presented To:- Dr. Surender Singh

2. A coupling reaction in organic chemistry is a general term for a variety of reactions where two hydrocarbon fragments are coupled with the aid of a metal catalyst. A Heck Reaction involves Conversion of Terminal alkene in an Internal alkene. Introduction

3. Prof . Akira Suzuki Prof . Richard F. Heck Prof . Ei-ichi Negishi The Nobel Prize was awarded jointly to Richard F. Heck, Ei-ichi Negishi and Akira Suzuki for Palladium- catalyzed C-C cross coupling reaction in 2010. Importance of C-C coupling Reaction

4. Mechanism Oxidative Addition –H Elimination   Reductive Elimination Insertion A B C D

5. The end