Histology of Stomach

Histology

1. 2 + 2 + STOMACH A dilated segment of the digestive tract. Main Function: To add fluid to the ingested food. Digestive System 1

2. rugae Ridges or folds of mucosa with submucosal core Allow stomach to distend upon the entry of food Digestive System 2

3. Digestive System 3 2 + 2 + REGIONS OF THE STOMACH Cardiac, Fundus, Body, and Pylorus

4. 2 + CARDIAC region Digestive System 4 ( A ): a simple columnar epithelium ( 1 ) forms broad crypts or foveolae ( 2 ). The mucous glands ( 3 The lamina muscularis mucosae is well developed. ( 4 ) Tela submucosa is a connective tissue layer embedding blood vessels and nerve complexes . ( 5 ) thick inner muscular layer is found The cardiac glands produce an alkaline mucus and lysozyme.

5. Digestive System 5 BODY

6. fundus Upper most curve of stomach located to the left of the cardia. Fig. Fundic stomach, dog.   Superficially, the gastric mucosa contains gastric pits, which form superficial invaginations and are lined by mucus-secreting columnar epithelial cells.  Deeper, the gastric glands are primarily composed of intermixed chief cells and parietal glands (fundus).   Digestive System 6

7. Digestive System 7 2 + 2 + Cell present in Body and Fundus

8. Digestive System 8

9. Isthmus mucous cell Types of cell In body and fundus Digestive System 9 Parietal (oxyntic) cells Produce the hydrochloric acid present in gastric juice. Secretes glycoprotein that binds with Vit B12 and facilitates its internal absorption. Present in the upper region of the gland in the transitional region between neck and the gastric pits. They secrete a neutral mucus that lines and protects the surface from secreted acid.

10. Mucous neck cell Types of cell In body and fundus Digestive System 10 Zymogenic/ Chief Cell Have all the characteristics of a protein synthesizing and exporting cell. In humans, they produce the enzymes pepsin and lipase. Present in clusters or single cell It has irregular in shape Secrete an acid mucus rich in glycosaminoglycans .

11. Argentaffin / Enterochromaffin cell Types of cell In body and fundus Digestive System 11 Other Endocrine cell (APUD) Affinity for chromium and silver salts Characterized by the presence of abundant dense secretory granules

12. Pylorus The cone-shaped constriction in the GI tract. the pylorus contains numerous   glands , including  gastric pits , which constitute about half the depth of the pyloric  mucosa . Digestive System 12

13. Principal layers of stomach

14. Digestive System 14

15. TITLE HERE 2 + MUCOSA SUBMUCOSA MUSCULARIS EXTERNA SEROSA Gastric pits Gastric gland Lamina propria Muscularis mucosa Loose connective tissue Contains the large blood and lymph vessels Spiral smooth fibers Longitudinal Circular oblique Covers the o uter portion of the stomach Mesothelium Thin lamina propria Digestive System 15

16. Digestive System 16

17. Digestive System 17

18. Digestive System 2 + SMALL INTESTINE Digestion of food is completed. 18

19. Digestive System 19 Presence of submucosal  brunner's glands Villi are rather flatter in the duodenum than in the jejunum, and plicae are less frequent. Longest and most "typical" region of the small intestine. Villi are rather longer and more finger-like in the jejunum than in the duodenum, and plicae are usually apparent. Has proportionally more  goblet cells  than more proximal sections of the small intestine.   The ileum also displays an increase in the amount of mucosal  lymphoid tissue , which forms conspicuous clusters of  lymph nodules , called  peyer's patches .