Definition of shock Shock defined as inadequate delivery of oxygen and nutrients to maintain normal tissue and cellular function. (Schwartz )
Epidemiology Shock occurs in 2% of all hospitalized patients in USA . Death usually occur due to complications rather than during hypotensive phase. Mortality in septic shock as low as 3% in previously health children and 6-9% in children with chronic illness .
Pathophysiology of shock Hypovolemic shock effective circulating blood volume Hemorrhage Truma venous return to heart Surgery cardiac output Burns blood flow Dehydration supply of oxygen Septic shock Anoxia Cardiogenic shock shock
Type Of Shock Hypovolemic shock Cardiogenic shock Distributive shock (tension pneumothorax ,cardiac tamponed ) Obstructive shock Septic shock
General clinical features Hypotension (SBP <100mmhg) Tachycardia>100/min Cold Rapid, Shallow respiration Drowsiness,confusion,irritability Oliguria(urine output<30 ml/h Multi organ failure
Hypovolemic shock Definition: I s an emergency condition in which severe blood and fluid loss make the heart unable to pump enough blood to the body . This type of shock can cause many organs to stop working .
P athophysiology Hemorrhage from small venules and veins (50%) Decreased filling of right heart Decreased filling of pulmonary vasculature Decreased f illing of left atrium and ventricle Left ventricular stroke volume decreases Drop in atrial blood pressure and tachycardia Poor perfusion to pulmonary arteries Cardiac depression and pump failure
Risk factors for hypovolemic shock
Classification of hypovolemic shock Hemorrhagic : Truma Gastrointestinal Bleeding Non Hemorrhagic : External fluid loss Diarrhea Vomiting Polyuria burns Anaphylaxis
Classification of acute blood loss
Compensatory Mechanisms Adrenergic discharge Hyperventilation Vasoactive hormones (angiotensin , vasopressin , epinephrine ) Re-absorption of fluid from interstitial tissue Resorption of fluid from intercellular to extracellular space Renal conservation of body water and electrolyte.
Signs and symptoms Restlessness Hypotension Cool Rapid and shallow respiration Hypothermia Thirst and dry mouth Distracted look in the eye
Diagnosis E valuation (agitation, cold Ext,tachycardia,hypotention)(25-30%B.Loss) Physical Exam: Ab,Chest ,Pelvic Hemorrhage (external , intrathoracic , intra Ab, Introperitoneal and long bon fracture) . Chest X-Ray Pelvic radiography Diagnostic ultrasound Diagnostic peritoneal lavage
Management objective : A: Increase cardiac output B: increase tissue perfusion The plan of action should be based on : A: primary problem (stop bleeding) B: Adequate fluid replacement c : blood transfusion ( Hb = 7 to 9) d: improving myocardial contractility e: correcting acid-base disturbances
Cont.… Resuscitation Immediate control of bleeding (rest , pressure Peking and surgical methods)] Infusion of fluid is the fundamental treatment Crystalloids fluid Colloids fluid (after crystalloid) Drugs : 1.sedatives 2.chronotropic agent 3.inotropic agent