SKIN ANATOMY AND PHYSIOLOGY Skin is the largest organ of the body It has 3 layers Epidermis Dermis Subcutaneous
Function Protection Sensation Endocrine Excretion Immunity Regulate temperature Fluid balance
Physical examination Assessing skin color Assessing rash Assessing skin lesion
Primary lesions Macule Flat , non palpable skin color change <1cm circumscribed border
Patch >1cm May have irregular border
Papule Elevated ,palpable solid mass with circumscribed border <0.5cm
Plaque Coalesced papule with flat top >0.5cm
Nodule Elevated ,palpable ,solid mass that extends deeper into the dermis than papule 0.5-2cm
Tumor Abnormal mass of tissue 1-2cm Eg .carcinoma
Vesicle Circumscribed ,elevated ,palpable mass containing serous fluid . <0.5 cm Eg .Herpes zoaster
Bullae Vesicle ,more than 0.5cm Eg.Pemphigus
Wheal Elevated mass with transient border,often irregular size and color vary Caused by movement of serous fluid into the dermis ,does not contain free fluid Eg . Urticaria and insect bite
Pustule Pus filled vesicle or bullae Eg.Acne ,impetigo
Cyst Encapsulated fluid filled or semisolid mass in the subcutaneous tissue Eg . Epidermoid cyst
Secondary lesions Results from changes in primary lesions Resulting from external trauma , infection,scratching
Erosions Loss of superficial epidermis that does not extend to dermis ,depressed and moist areas. Eg . Ruptured Vesicle
Ulcer Skin loss extending epidermis ,bleeding and scaring
Fissures Linear crack in the skin that may extend to dermis
Crust Dried residue of serum ,blood or pus on skin surface
Scar Skin mark left after healing of a wound or region Young scar –red and purple Mature –white or glisterring
Vascular lesions Petechiae Round, red or purple macules Secondary to blood extravasation associated with bleeding , tenderness or emboli to skin
Ecchymosis Round or irregular macular lesion ,larger than petechia Color varies and changes black,yellow and green Associated with trauma,bleeding tendencies
Cherry angioma Papular and round ,red or purple Noted on trunk ,extremities ,may blanches with pressure