Inflammation and its mechanism

presented by HAFIZ M WASEEM
university of education LAHORE Pakistan
i am from mailsi vehari and studied in lahore
bsc in science college multan
msc from lahore

1. Education University LMC Lahore Inflammation and its Mechanism

2. HAFIZ M WASEEM UNIVERSITY OF EDUCATION LAHORE

3. Inflammation refers to your body’s process of fighting against things that harm it, such as infection, toxins, in an attempt to heal itself When something damages your cell your body releases a response chemicals that trigger a response from your immune system Without inflammation wounds go unchecked never heal Intrduction

4. 1793- John Hunter described that inflammation is not a disease it is salutary effect on host 1893- Conheihm used microscope to observe changes in vessels 1880- Metchinkoff discovered phagocytosis Paul Ehrilch proposed humoral theory of immunity 1924- Lewis explained role of chemical mediators in inflammation Historical Highlights

5. Mechanism of Inflammation

6. Causes of inflammation Infective agents like bacteria, viruses and their toxins, fungi parasites Immunological agents like cell-mediated and antigen-antibody reactions Physical agents like heat, cold, radiation, mechanical trauma Chemical agents like organic and inorganic poisons Inert materials such as foreign bodies

7. Types of Inflammation

8. Acute inflammation is a short- term process occuring in response to tissue injury, usually appearing within few minutes or hours Cellular Events Margination Adhesion Emigration Chemotaxis Phagocytosis Mediators Histamines Serotins Plasmins Adrenalins and Non Adrenalins Neutrophilic Proteases Actue Inflammation

9. Chronic Inflammation Chronic inflammation is the ability of body to repair and overcome the damage and it is vary with the cause of inflammation It is Slow, long-term lasting for prolonged periods of several months to years Granulomatous Chronic inflammation Non Granulomatous Chronic inflammation

10. Goals To get rid of initial cause of cell injury To get rid of consequences of injury To prevent other organ system damage Initiate the process of repair

11. References https://www.slideshare.net/mobile/AmritJaishi/inflammation-75876889 https://www.slideshare.net/mobile/BilalDear1/acute-inflammationpathology https://en.m.wikipedia.org/wiki/Inflammationhttps://pubmed.ncbi.nlm.nih.gov/18240538 /https://www.medscape.com/answers/325370-155833/