Intravenous route of drug administration

intravenus route f drug administration,
prepared by Ashish kumar sharma
bpt 2nd year
Noida international university

1. INTRAVENOUS ROUTE OF DRUG ADMINISTRATION Prepared By- Ashish kumar Sharma BPT 2 nd year

2. Definition Intravenous route is a systematic route of drug administration in which the drug is directly given into the blood stream through veins.

3. Drug can be given intravenously as ;- Bolus Slow I.V Injection I.V Infusion

4. Advantages of I.v routes 100% Bioavailability Quick onset of action Large volume of fluids Highly irritant drugs (Anti cancer drug) Hypertonic Solution (20% Manitol) Constant plasma level can be maintained by Infusion.

5. DISADVANTAGES OF IV ROUTES Phlebitis (Inflammation of vein) Self administration is not possible Strict Aseptic Condition needed Injury narcosis of tissue Depot preparation can not be given

6. SIDE EFFECTS Infection Damage to blood vessels and injection site Air embolism Blood clots

7. PHARMACOKINETICS It is the study of time, course of drug absorption, distribution, Metabolism and excretion.

8. pharmacodynamics Pharmacodynamics is the study of drug effects. It states that how does the drug is effecting towards the body .

9. Many different types of medications can be given by IV. Some of the drugs more commonly given by this method include

10. SOME COMMONLY USED i.V 0.9% Normal saline (NS, 0.9NaCl, or NSS) Lactated Ringers (LR) or Ringers Lactate (RL) 5% Dextrose in water (D5 or D5W) 0.45% Normal saline (Half Normal saline, 0.45NaCl, .45NS)

11. Chemotherapy drugs such as:- Doxorubicin Vincristine Cisplatin Paclitaxe

12. Antibiotics such as:- Vancomycin Meropenem Gentamicin

13. antifungal drugs such as Micafungin Amphotericin

14. pain medications such as:- Hydromorphone Morphine

15. drugs for low blood pressure such as:- Dopamine Epinephrine Norepinephrine Dobutamine

16. THANK YOU