Introduction to endocrine pharmacology ppt

14 views 10 slides May 09, 2025
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About This Presentation

Composed of glands like the pituitary, thyroid, adrenal glands, pancreas, gonads, etc.
Endocrine glands are tissues or organs that excrete chemical substances (hormones) directly into the blood.
Common endocrine glands are the hypothalamus, pineal, adrenal glands pituitary, thyroid, pancreas and go...


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Endocrine Pharmacology Introduction to

What Is the Endocrine System? Composed of glands like the pituitary, thyroid, adrenal glands, pancreas, gonads, etc . Endocrine glands are tissues or organs that excrete chemical substances (hormones) directly into the blood. Common endocrine glands are the hypothalamus, pineal, adrenal glands pituitary, thyroid , pancreas and gonads. Endocrine glands secrete hormones directly into the bloodstream or into the intercellular space, allowing the hormones to reach their target . Functions via hormones, which are chemical messengers . Maintains homeostasis, metabolism, growth, and reproduction.

What Is the Hormone? Hormone is a substance produced by specialized cells in specific glands and transported to a distance where it acts on target tissues . Endocrine system function s via hormones which are chemical messengers.

Types of Hormones 1. Peptides: Hypothalamic regulatory hormones, pituitary hormones, insulin, glucagon , parathyroid hormones . 2 . Steroids: Adrenocortical hormones, sex steroids . 3 . Catecholamines : Adrenaline, noradrenaline . 4 . Others: Thyroxine (T₄), triiodothyronine (T₃).

Site and Mode of Action of Hormones They act on their specific receptors situated : On the cell membrane In the cytoplasm In the nucleus

On the cell membrane Some hormones bind with the cell membrane receptors and increase cAMP concentration, e.g. catecholamines , most of the peptide hormones . Some hormones cause inhibition of cAMP production by binding to cell membrane receptors, e.g. somatostatin .

On the Cytoplasm

On the Nucleus

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