ANAEMIA
Anaemia is a widely prevalent disorder affecting over half a billion women of reproductive age
(WRA) and over quarter of a billion children under 5 years old worldwide. It is a condition in which
red blood cells have fewer haemoglobin molecules than normal, or fewer red blood cells overall,
and thus less ability to carry oxygen to tissues in the body.The word anaemia derives from ancient
Greek meaning “lack of blood” and blood haemoglobin concentration is the most reliable and
commonlyusedsingleindicatorofanaemia.Iron(“haeme”)iscentraltothehaemoglobinmolecule.
A worldwide systematic analysis indicated that the global prevalence of anaemia among children
under 5 years was 47%, pregnant women 43%, and non-pregnantWRA 33%, while the prevalences
in South Asia were much higher: children under 5 years 70% and both pregnant and non-pregnant
WRA53% .
Anaemia causes fatigue and low productivity and adversely affects cognitive and motor
development. It contributes to over 100,000 maternal and almost 600,000 perinatal deaths
worldwide each year, as well as risk of pre-term delivery and low birth weight in newborns and
reduced cognitive development and therefore school performance in children. These in turn lead
tosocialandeconomiclosses,thelatteramountingtoabout4%ofGDPglobally.
Iron deficiency from diets poor in iron account for around 50% of anaemia. A study estimated that
25% of all anaemia among children under 5 years and 37% among non-pregnant WRA was due to
iron deficiency. Others estimated that 42% of anaemia in children would be amenable to iron
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WHO.The global prevalence of anaemia in 2011. Geneva:World Health Organization;2015.
Klemm R, Sommerfelt AE, Boyo A, Barba C, Kotecha P, Steffen M, and FranklinN. Are We Making Progress on Reducing
Anemia in Women? Cross-country Comparison of AnemiaPrevalence, Reach, and Use of Antenatal Care and Anemia
Reduction Interventions. AED, June 2011.
Stevens GA, Finucane MM, De-Regil LM, Paciorek CJ, Flaxman SR, Branca F, Peña-Rosas JP, Bhutta ZA, Ezzati M on behalf
of Nutrition Impact Model Study Group (Anaemia). Global, regional, and national trends in haemoglobin concentration
and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995-2011: a
systematic analysis of population-representative data. Lancet Global Health (1) e16-25, 2013.
IbidWHO, Klemm et al., Stevens et al.
Horton S, Ross J. The economics of iron deficiency. Food Policy 28:51-75, 2003.
DeMaeyer E, Adiels-Tegman M.The prevalence of anaemia in the world.World Health Statistics Quarterly, 1985.
Petry N, Olofin I, Hurrell RF, Boy E,Wirth JP, Moursi M, Donahue Angel M, Rohner F.The Proportion of Anemia Associated
with Iron Deficiency in Low, Medium, and High Human Development Index Countries: A Systematic Analysis of National
Surveys. Nutrients Nov 2; 8(11), 2016.
Ozkasap S, Yarali N, Isik P, Bay A, Kara A, Tunc B. The Role of Prohepcidin in Anemia due to infection.
Pediatr Hematol Oncol 2013.
Helicobacter Pylori
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BACKGROUND