Definition of jaundice Fear of the body to excrete bile pigment result in accumulation of pigment in the blood plasma term hyperbelerobenia this can result from a description of the flow of bile through the common bilect or hepatic duct by obstruction that is gallstone allowing while to build up in the blood
2. Jaundice it is otherwise called icterus. A yellowish s training of the skin , Sclerae and deeper ti ssue with bile which are increased in plasma , can be seen on examination at serum b ilirubin level 27 to 35 I mol/L ( 1.5 – 2 mg/dl ).
1. Hemolytic jaundice It is due to an increase breakdown of red blood cells which produce an increase amount of unconjugated bili rubin in the blood .
2.Hepatocellular jaundice It is due to result from the liver altered ability to take up bilirubin from the blood or to conjugated or excrete it in hepatocellular disease the hepatocytes are damage and leak bilirubin .
3. Obstructive Jaundice It is due to decrease or o bstructive flow of bile through the liver or b illiary duct system .
4. Hereditary It is due to increase Bluetooth and level result from any of several in Heritage dis turb ance like rotor syndrome and Gilbert syndrome
Etiology Hemolysis congenital defect like ( Gillb er t syndrome , crigler Naja r ) Hepatitis toxins Agents, Alcoholoic hepatitis
Clinical manifestation Yellow colour of skin mucus membrane , eyes , nail beds and tongue light coloured Sto ol yellowish brown colour urine
Diagnostic evaluation History collection – colo u r of stool and urine drugs recent blood transfusion alcohol intake contact with hepatitis infection occupation and anaemia
Physical examination P ale yellow V/S de ep yellow s ign of cirrhosis liver tender in large , f i rm , irregular gallbladder tender splenomegaly
Medical management Symptomatic treatment pain relief Tr eatment of dehydration correction of co a g u lopathy Treat secondary complications Sepsis , bleeding , An aemia Treat underline cause Di etary management