Lasix (Furosemide Tablets)

Lasix tablets (Furosemide) is mainly used for the treatment of high blood pressure and edema.

1. Lasix Tablets
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Lasix tablets (Furosemide) is mainly used for the
treatment of two conditions: High blood pressure
and edema. Furosemide works by causing the
kidneys to get rid of unneeded water and salt
from the body into the urine.

2. Lasix Tablets
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Lasix Tablets are manufactured by
Sanofi Aventis (Sanofi India Limited).
(Website: sanofi-aventis.com)

3. Furosemide Tablets – Brand Names
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Furosemide tablets are available as
Lasix, Frusenex , Tebemid, Urix and
Salinex.

4. Active Ingredient
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The active ingredient contained in Lasix
tablets is Furosemide.

5. Chemical Structure
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The structure of Furosemide is given below:

6. Uses of Lasix Tablets
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Lasix Tablets ( Furosemide ) in the treatment of
used to treat fluid build-up due to congestive heart
failure, edema, liver scarring, or kidney disease.
Furosemide may also be used for the treatment of
high blood pressure.
The amount of medication required depends on the
patient undergoing treatment. Edema is associated
with heart failure, hepatic cirrhosis, renal
impairment, nephrotic syndrome. Lasix tablets
are also used in cerebral/pulmonary edema
where rapid diuresis is required. Furosemide
tablets are also sometimes used in the treatment of
severe hypercalcemia in combination with
adequate rehydration.

7. Storage Instructions

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Lasix (Furosemide tablets ) have to be
stored at controlled room temperature
i.e. below 25°C (77°F). Keep in a cool
dark place away from light.
Keep this as well as all other medicines
away from children and pets.

8. Lasix Dosage

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➢ The usual initial dose of Lasix tablets for the
treatment of Edema in adults is 20 to 80 mg
given as a single dose. Normally a prompt
diuresis ensues. If required, the same dose can
be administered 6 to 8 hours later or the dose
may be increased. The dose can be raised by
20 or 40 mg if required and given not sooner
than 6 to 8 hours after the previous dose until
the desired diuretic effect has been obtained.
The dosage of Lasix tablets (Furosemide) is
given below:

9. Lasix Dosage

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➢ The usual starting dose of Lasix tablets for
the treatment of hypertension in Adults is 80
mg, usually divided into 40 mg twice a day.
Dosage should then be adjusted as per the
therapeutic response of the individual patient.
If response is not satisfactory, other anti-
hypertensive agents should be added.
The dosage of Lasix tablets (Furosemide) is
given below:

10. Warnings

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Excessive diuresis can result in
dehydration and reduction in blood
volume with circulatory collapse and
with the possibility of vascular
thrombosis and embolism, specially in
elderly patients.
Excessive loss of potassium in
patients that receive cardiac
glycosides may precipitate digitalis
toxicity.

11. Warnings

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Some side effects for example an
undesirable drop in blood pressure
may impair the patient’s ability to
concentrate and react and therefore
constitute a risk in situations where
these abilities are of special importance
(e.g. operating a vehicle or machinery).

12. Lasix Tablets
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Contraindications
Lasix is contraindicated in patients with a
hypersensitivity to Furosemide or any other
component of this medication.
Patients allergic to Sulfonamides (e.g.
sulfonamide antibiotics or sulfonylureas) can also
show cross-sensitivity to Lasix.
Lasix is also contraindicated in cases of
Complete renal shutdown; impaired renal function
or anuria.
If increasing azotaemia and oliguria occur during
treatment of severe progressive renal disease,
discontinue Furosemide tablets.

13. Lasix Tablets
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Contraindications
Severe hypokalaemia, hyponatraemia,
hypovolaemia, dehydration or hypotension must be
regarded as contraindications until serum
electrolytes, fluid balance and blood pressure have
been restored to normal levels.
In hepatic coma or precoma and conditions
producing electrolyte depletion, Furosemide
therapy should not be started until the underlying
conditions have been corrected or ameliorated.
Furosemide is contraindicated in pregnant and
breast-feeding women.
Do not administer Furosemide to newborns
presenting jaundice or to infants with conditions
which might induce hyperbilirubinaemia or
kernicterus.

14. Lasix Side Effects
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➢
The common side effects of Lasix
tablets can include electrolyte
disturbances (including symptomatic),
dehydration and hypovolaemia especially
in elderly patients, increased blood
creatinine, increased blood triglycerides,
hyponatremia, hypochloremia,
hypokalaemia, blood cholesterol
increased blood uric acid increased,
attacks of gout, and urine volume
increased.

15. Lasix Overdose
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Symptoms of Lasix overdose can include
Decreased urination, drowsiness,
increase in heart rate, irregular heartbeat,
irritability, mood changes, muscle
cramps, numbness, tingling, pain, or
weakness in the hands, feet, or lips, rapid
breathing, seizures, sunken eyes,
thirst, trembling, weak pulse, weakness
and heaviness of the legs and wrinkled
skin.

16. Lasix Overdose
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No specific antidote to Lasix is currently
known. If ingestion has only just taken
place, attempts may be made to limit
further systemic absorption of the active
ingredient by measures such as activated
charcoal.
Treatment of Lasix overdosage is
supportive and consists of replacement
of excessive fluid and electrolyte losses.

17. Lasix During Pregnancy
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Lasix (Furosemide Tablets) has been
classified by the US FDA as Pregnancy
Category C.
Lasix must not be given during
pregnancy unless there are compelling
medical reasons to do so.
Lasix treatment during pregnancy requires
frequent monitoring of foetal growth.

18. Lasix Tablets
For more details on
Lasix Tablets click here
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Lasix Tablets (Furosemide) by Sanofi
India Limited.