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genetic history

1. HISTORIA DE  LA GENÉTICA Sara Mariam Fontal Montoya  Sofia Guerra Bautista  Andrés Felipe Ceballos Álvarez Juan Sebastian 2702

2. CONTENIDOS 01 Desarrollo histórico de la genética humana 02 03 04 05 06 Herencia (Personajes relevantes) Medicina genómica Desarrollo histórico de la genética humana Proyecto genóma humano Dimensiones del ADN

3. DESARROLLO HISTÓRICO DE LA GENÉTICA HUMANA La genética : estudio de la herencia y la variación de los seres vivos . La genética humana : desafíos únicos por la complejidad de la especie .   Los inicios Gregor Mendel (1865): leyes de la herencia . Bases para comprender los mecanismos básicos de la herencia . Juan Gregorio Mendel

4. Siglo XX: Un siglo de avances Archibald Garrod: conexión entre genes y enzimas . Thomas Hunt Morgan: recombinación genética y mapas de ligamiento . La molécula de la vida James D. Watson y Francis H. C. Crick (1953): modelo de doble hélice del ADN. Permitió el desarrollo de técnicas para manipular el ADN. Archibald Garrod (1858-1935).

5. James D. Watson Thomas H. Morgan

6. El Proyecto Genoma Humano Secuenciación completa del ADN humano (1990-2003). Un logro sin precedentes en la historia de la ciencia . Aplicaciones de la genética humana Medicina: diagnóstico , tratamiento y prevención de enfermedades . Derecho y ciencia política : pruebas de paternidad , análisis de crímenes . Psicología : comprensión del comportamiento humano . Repercusiones y desafíos Beneficios : avances en medicina , agricultura , biotecnología . Posibles perjuicios : discriminación genética , eugenesia .

7. DIMENSIONES DEL ADN Durante  mucho tiempo se tenían algunas dudas sobre el ADN y estas fueron respuestas en el lapso de 1955-1975. Una de ellas eras: ¿ cuántas moléculas de ADN hay en un cromosoma ? ¿ cuáles eran sus dimensiones ? ¿ cómo se encontraba dispuesto en los cromosomas ?

8. HERENCIA , desoxirribosa y bases nitrogenadas  Adenina   A Timina   T Guanina G Citosina C

9. HERENCIA Los  componentes  del ADN: grupos   fosfato ,  desoxirribosa  y bases  nitrogenadas   Adenina   A Timina   T Guanina G Citosina C

10. PERSONAJES RELEVANTES Variaciones en la secuencia del ADN Termino "código" Da origen al código genético George Gamow (1904-1968)   Francis Crick y Sydney brenner (1966)

11. PERSONAJES RELEVANTES Inventan el termino ARN "mensajero" (ARNm) Marsall Nirenberg/ Har G.Khorana/ Severo Ochoa  

12. PROYECTO GENOMA HUMANO 1980-1990/2003

13. El Instituto Nacional de la Salud (NIH) y el Departamento de Energía (DOE) de Estados Unidos. Este proyecto , que comenzó oficialmente en 1990, En el año 2001, este proyecto llevaba consumidos alrededor de 3.000 millones de dólares . Celera y Presidida por el investigador Craig Venter había logrado en el año 2000 fue realizado con el ADN de sólo cinco personas.

14. ¿QUÉ ES LA MEDICINA GENÓMICA? Rama de la medicina que se enfoca en el estudio de los genes y sus funciones en relación con la salud y las enfermedades . Busca comprender cómo las variaciones genéticas pueden influir en la respuesta a los tratamientos médicos .

15. Es relativamente nueva , surge como ciencia , a partir del proyecto de genóma humano . Después de lograr   secuenciar por primera vez el genóma humano , se empezo la busqueda e implementación de estas habilidades para la medicina . ¿CUÁNDO SURGE LA MEDICINA GENÓMICA?

16. La medicina genómica nos permite hacer tratamientos mas específicos y efectos , dependiendo de la genética del paciente . Con ella se  puede ser más preciso en cuanto a tratamientos y estudios de los pacientes . Sirve para  identificar   variantes genéticas que se relacionan a enfermedades . ¿POR QUÉ ES IMPORTANTE LA MEDICINA GENÓMICA?

17. PERSONAJES RELEVANTES Química . Trabajo con difracción de rayos X, crucial para la determinación de la estructura de ADN Biologos moleculares . Determinaron la estructura del ADN en 1953, base de la genética actual. James Watson (1928-Actualidad) y Francis Crick (1916-2004) Rosalind Franklin (1920-1958)

18. PERSONAJES RELEVANTES Genetista . Líder del proyecto de genóma humano   en 2003 Genetista   conocido por el desarrollo de tecnologías para la secuencialización del ADN y su aplicación medica, como la modificación genética . George Church (1954-Actualidad) Francis Collins (1950-Actualidad)

19. Venus has extremely high temperatures Neptune is very far away from the Sun REVIEWING CONCEPTS Mars is actually a very cold place Mercury is the closest planet to the Sun Saturn is a gas giant with several rings Jupiter is the biggest planet of them all MARS VENUS NEPTUNE MERCURY SATURN JUPITER

20. A PICTURE IS WORTH A THOUSAND WORDS

21. A PICTURE ALWAYS REINFORCES THE CONCEPT Images reveal large amounts of data, so remember: use an image instead of a long text. Your audience will appreciate it

22. NAME OF THE SECTION You can enter a subtitle here if you need it 02

23. 4,498, 300,000 Big numbers catch your audience’s attention

24. Jupiter's rotation period 9h 55m 23s 333,000 The Sun’s mass compared to Earth’s 386,000 km Distance between Earth and the Moon

25. Mercury is the closest planet to the Sun and the smallest of them all MERCURY Venus has a beautiful name and is the second planet from the Sun VENUS Despite being red, Mars is actually a cold place. It’s full of iron oxide dust MARS LET’S USE SOME PERCENTAGES 50% 75% 25%

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29. VENUS NEPTUNE MERCURY THIS IS A MAP Venus is the second planet from the Sun Neptune is very far away from the Sun Mercury is the closest planet to the Sun

30. A TIMELINE WORKS WELL MERCURY Mercury is the closest planet to the Sun JUPITER Jupiter is the biggest planet of them all MARS Despite being red, Mars is a very cold place VENUS Venus is the second planet from the Sun 01 02 03 04

31. YOU CAN USE THIS GRAPH Follow the link in the graph to modify its data and then paste the new one here. For more info, click here Mercury is the smallest planet Jupiter is the biggest planet Earth is the planet with life Saturn is a gas giant with rings 50% 40 % 30% 60 %

32. CENTROMERE Venus has extremely high temperatures SHORT ARM Mars is actually a very cold place Jupiter is the biggest planet of them all LONG ARM Saturn is a gas giant and has several rings TELOMERE VISUALIZE YOUR IDEAS

33. TABLES REPRESENT YOUR DATA MASS DIAMETER SURFACE MERCURY 0.06 0.38 0.38 MARS 0.11 0.53 0.38 SATURN 95.2 9.4 1.16

34. CHECK OUT YOUR DATA Follow the link in the graph to modify its data and then paste the new one here. For more info, click here Saturn is a gas giant with rings Jupiter is the biggest planet Mercury is the smallest planet Earth is the planet with life 2 0% 40% 10% 30 %

35. EXPERTS’ OPINIONS Saturn is a gas giant and has several rings Mercury is the closest planet to the Sun Despite being red, Mars is a very cold place —NICOLE RAGAN —MATTHEW ROE —BEN ELLIS

36. ORDER YOUR INFORMATION COLUMN 1 COLUMN 2 COLUMN 3 MERCURY Mercury is the closest planet to the Sun 20XX JUPITER Jupiter is the biggest planet of them all 20XX MARS Mars is a very cold place 20XX VENUS Venus is the second planet from the Sun 20XX

37. PRIORITIZE THE PAPERS VENUS NEPTUNE MERCURY Venus is the second planet from the Sun Neptune is very far away from the Sun Mercury is the closest planet to the Sun JUPITER SATURN MARS

38. AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher AUTHOR (YEAR). Title of the publication . Publisher BIBLIOGRAPHY OF INTEREST

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