Levonorgestrel how it works, uses, side effects aa sraw

Levonorgestrel powder is used for emergency contraception. It provides a safe and effective way to prevent an unintended pregnancy after unprotected sex or contraceptive failure.

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Levonorgestrel:Howitworks,uses,sideeffects-AASraw
Content
Levonorgestrel:Howitworks,uses,sideeffects-AASraw
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1.WhatisLevonorgestrelpowder?
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2.LevonorgestrelBenefits
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3.HowdoesLevonorgestrelwork?
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4.Whatdosageoflevonorgestrelyoushouldtake?
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5.WhatyoushouldtofollowifmissedLevonorgestreldosage?
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6.Whatarethesideeffectsoflevonorgestrel?
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7.WhatyoushouldknowbeforeusingLevonorgestrel?
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1.WhatisLevonorgestrelpowder?
Levonorgestrelpowderisaaprogestinthatisusedascontraception,soldunderthe
brandnamePlanBamongothers.Itisusefulwithin120hoursasemergencybirth
controlafterunprotectedsexorafterfailureofanotherbirthcontrolmethod(suchas
condombreakage,ormissing2ormorebirthcontrolpills).Itworksbypreventinga
woman'seggfromfullydeveloping.Itmayalsopreventtheattachmentofthewoman's
eggtothewalloftheuterus.butitwillnotpreventthespreadofhuman
immunodeficiencyvirus(HIV,thevirusthatcausesacquiredimmunodeficiency
syndrome[AIDS])andothersexuallytransmitteddiseases.LevonorgestrelCAS:
797-63-7ismarketedmostlyasacombinationoralcontraceptiveunderseveralbrand
namessuchasAlesse,Triphasil,andMin-Ovral.Itiseffectiveforlong-termpreventionof
pregnancy.

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Chemicalname: Levonorgestrelpowder
CAS: 797-63-7
EINECS: 212-349-8
MolecularFormula:C21H28O2
MolecularWeight:312.45
Purity: 99%min
Synonyms:
13-ethyl-17-alpha-ethynyl-17-beta-hydroxy-4-gonen-3-one;
13-ethyl-17-alpha-ethynylgon-4-en-17-beta-ol-3-one;
13-ethyl-17-hydroxy-19-dinor-17-alpha-pregn-4-en-20-yn-3-on(+)-1;
17-alpha-ethinyl-13-beta-ethyl-17-beta-hydroxy-4-estren-3-one;
17-beta-hydroxy-18-methyl-19-nor-17-alpha-pregn-4-en-20-yn-3-on;
17-ethynyl-18-methyl-19-nortestosteron;
17-ethynyl-18-methyl-19-nortestosterone;
18-methyl-17-alpha-ethynyl-19-nortestosterone
Meltingpoint: 206°C
BoilingPoint: 459.1°Cat760mmHg
FlashPoint: 195.4°C
StorageTemp: 2-8°C
Color: Whitecrystallinepowder

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2.LevonorgestrelBenefits
LevonorgestrelCAS:797-63-7givestheusersmanynon-contraceptivebenefits:the
amountofmenstrualbleedingandthenumberofdaysofmenstrualbleedingare
reduced,whichmakesitsuitableforthetreatmentofmenorrhagia(heavymenstrual
bloodloss).
Dysmenorrhoea(painfulmenstruation)andpremenstrualsymptomsarealsorelieved.In
addition,Levonorgestrelprovidesprotectionfortheendometriumduringhormone
replacementtherapy.Thelocalreleaseoflevonorgestrelintotheuterinecavityresultsin
astronguniformsuppressionoftheendometrialepitheliumastheepitheliumbecomes

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insensitivetoestradiolreleasedfromtheovaries.Thisaccountsforthereductionin
menstrualbloodloss.Allpossiblepatternsofbleedingareseenamongusersof
Levonorgestrel;however,mostofthewomenwhoexperiencetotalamenorrhoea
continuetoovulate.Thefirstmonthsofuseareoftencharacterisedbyirregular,scanty
bleeding,whichinmostcasesresolvesspontaneously.Themenstrualpatternand
fertilityreturntonormalsoonafterLevonorgestrelisremoved.Thecontraceptive
efficacyishighwith5-yearfailureratesof0.5-1.1per100users.Theabsolutenumberof
ectopicpregnanciesislow,asistherateper1000users.Levonorgestrelisequally
effectiveinallagegroupsandthebodyweightoftheuserisnotassociatedwithfailure
ofthemethod.InWesternculturescontinuanceratesamongusersof
LevonorgestrelCAS:797-63-7arecomparablewiththoseofotherlong-termmethods
ofcontraception.Prematureremovalofthedeviceismostoftenassociatedwithheavy
menstrualbleedingandpain,aswithotherlong-termmethodsofcontraception,andis
mostcommonintheyoungestagegroup.Whenadequatelycounselledaboutthe
benignnatureofoligo-oramenorrhoea,mostwomenareverywillingtoacceptlife
withoutmenstruation.Theriskofprematureremovalcanbemarkedlydiminishedwith
goodpre-insertioncounselling,whichalsomarkedlyincreasesusersatisfaction.User
satisfactionisstronglyassociatedwiththeinformationgivenatthetimeof
Levonorgestrelinsertion.Thus,thebenefitsofthelevonorgestrelmakeitaverysuitable
methodofcontraceptionformostwomen.

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3.HowdoesLevonorgestrelwork?
LevonorgestrelCAS:797-63-7comesasatablettotakebymouth.Ifyouaretaking
levonorgestrelasasingletabletproduct,takeonetabletassoonaspossiblewithin72
hours(3days)afterunprotectedsexualintercourse.Ifyouaretakinglevonorgestrelasa
twotabletproduct,takeonetabletassoonaspossiblewithin72hoursafterunprotected
sexualintercourseandtakeaseconddose12hourslater.Levonorgestrelworksbestifit
istakenassoonaspossibleafterunprotectedsexualintercourse.Ifyouvomitlessthan
2hoursafteryoutakeadoseoflevonorgestrel,contactyourdoctortoaskifyouneed
torepeatthedose.Afteryoutakethismedication,thetimewhenyourperiodcomesand
howmuchyoubleedmaychange.Tellyourdoctorrightawayifyourperiodismorethan
7dayslate.Youmayneedtotakeapregnancytest.Ifyouaretakingthe
over-the-counterproducttoself-treat,readalldirectionsontheproductpackagebefore
takingthismedication.Ifyouhaveanyquestions,talktoyourpharmacist.Ifyourdoctor
hasprescribedthismedication,takeitasdirected.Thismedicationmaynotworkwellin
womenoveracertainweight(forexample,greaterthan164poundsor74kilograms),or
ifyouhaveusedcertainothermedicationswithinthepastmonth.Thiseffectcanresult
inpregnancy.Talktoyourdoctorformoredetailsandtoseeifthismedicationisright
foryou(seealsoDrugInteractionssection).
LevonorgestrelCAS:797-63-7maybeprescribedforotheruses.Askyourdoctoror
pharmacistformoreinformation.

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4.Whatdosageoflevonorgestrelyoushouldtake?
LevonorgestrelCAS:797-63-7comesinpillformandadoseof1.5mgmustbetakennot
morethan72hoursafterintercourse.Itismosteffectivewithin24hours.
Singledoseregimen:Takeone1.5mgtabletassoonaspossiblewithin72hoursof
unprotectedsexorwhenbirthcontrolfails.
Two-doseregimen:Takeone0.75mgtabletassoonaspossiblewithin72hoursof
unprotectedsexorwhenbirthcontrolfails,followedbyasecond0.75mgtablet12
hourslater.

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5.WhatyoushouldtofollowifmissedLevonorgestreldosage?
Readandfollowtheseinstructionscarefullyasmissingdosagewillincreasesyourrisk
ofbecomingpregnant.andcallyourdoctorifyouhaveanyquestions.
Ifyoumissoneactivepill,takeitassoonasyoucan.Thentakeyournextpillatthe
regulartime.Thismeansyoumaytaketwopillsinoneday.Ifyoumisstwoactivepills
inweek1or2,taketwopillsassoonasyoucanandtwomorepillsthenextday.
Continuetakingonepilladayuntilyoufinishthepack.Useanotherkindofbirthcontrol
forsevendaysafteryoumissadose.IfyoumisstwoactivepillsinarowinWeek3:Day
1start—Throwouttherestofyourpillsandstartanewpackonthesameday.Sunday
start—ContinuetakingonepilladayuntilSunday,thenthrowouttherestofthepack
andstartanewpackthatsameday.IfyoumissthreeactivepillsinarowinWeek1,2,
or3,throwouttherestofthepackandstartanewpackonthesamedayifyouarea
Day1starter.IfyouareaSundaystarter,keeptakingapilleverydayuntilSunday.On
Sunday,throwouttherestofthepackandstartanewpackthatday.Ifyoumisstwoor
moreactivepills,youmaynothaveaperiodduringthemonth.Ifyoumissaperiodfor
twomonthsinarow,callyourdoctorbecauseyoumightbepregnant.Ifyoumissa
reminderpill,throwitawayandkeeptakingonereminderpillperdayuntilthepackis
empty.Themorepillsyoumiss,themorelikelyyouaretohavebleeding.Ifyoumisstwo
periodsinarow,callyourdoctorforapregnancytestbeforeyoutakeanymorepills.

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StoreLevonorgestrelCAS:797-63-7inaclosedcontaineratroomtemperature,away
fromheat,moisture,anddirectlight.
6.Whatarethesideeffectsoflevonorgestrel?
LevonorgestrelCAS:797-63-7maycausesomeadverseeffectswhenusedasan
emergencycontraceptive.Checkwithyourdoctororpharmacistimmediatelyifanyof
thefollowingsideeffectsoccur:
Commonsideeffectsoflevonorgestrelcaninclude:
Fatigue
Dizziness
Depression
mildbloating
Liverproblems
Weightchanges
Allergicreactions
Breasttenderness
Headacheormigraine
Lossofinterestinsex
Abdominalorpelvicpain
Upsetstomach;feelingorbeingsick

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Irregularvaginalbleedingorspotting
longerorheaviermenstrualperiods
stoppingofmenstrualbleeding
uterinebleedingbetweenmenstrualperiods
Lessserioussideeffectsoflevonorgestrelmayinclude:
headache,nausea,diarrhea,orstomachpain;
dizziness,tiredfeeling;
cramps
paleskin
Blurredvision
nervousness
sloworfastheartbeat
breastpainortenderness;
troubledbreathingwithexertion
unusualtirednessorweakness
unusualbleedingorbruising
itchingofthevaginaorgenitalarea
whiteorbrownishvaginaldischarge
thick,whitevaginaldischargewithmildornoodor
Moreserioussideeffectsthatdorequiremedicalattentioncaninclude:

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Genitalsores
Highbloodpressure
Signsofpregnancy
Feverorflu-likesymptoms
severecrampsorpelvicpain;
Severeorsuddenheadache
Severeabdominalpain
Suddenshortnessofbreath
Yellowingoftheskinoreyes
Pain,swellingorwarmthintheleg
painduringsexualintercourse;
Difficultywithtalking,walkingorbalance
Nomenstrualperiodforsixweeksduringuse
paleskin,weakness,easybruisingorbleeding;
heavyorongoingvaginalbleeding,vaginalsores,vaginaldischargethatis
watery,foul-smellingdischarge,orotherwiseunusual;
severepaininyoursideorlowerstomach;
Swellingofface,lips,eyelids,tongue,handsandfeetAllergicreactionssuchas
skinrash,itching,hives,or
swellingoftheface,lipsortongue

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Thisisnotacompletelistofsideeffectsandothersmayoccur.Tellyourdoctoror
pharmacistaboutanyunusualorbothersomesideeffect.Youmayreportsideeffectsto
FDAat1-800-FDA-1088.
7.WhatyoushouldknowbeforeusingLevonorgestrel?
BeforeusingLevonorgestrelCAS:797-63-7,therisksoftakingLevonorgestrelmustbe
weighedagainstthegooditwilldo.Thisisadecisionyouandyourdoctorwillmake.For
thismedicine,thefollowingshouldbeconsidered:
Existingpregnancy—
Levonorgestrelshouldnotbeusedifyouarealreadypregnantorplanningapregnancy

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innearfuture.Chancesofapre-existingpregnancyshouldberuledoutbeforetaking
thismedicine.
Breast-feeding—
Therearenoadequatestudiesinwomenfordetermininginfantriskwhenusing
Levonorgestrelduringbreastfeeding.Weighthepotentialbenefitsagainstthepotential
risksbeforetakingLevonorgestrelwhilebreastfeeding.
Weightgain—
UseofLevonorgestrelcancausemoderatetosignificantweightgainandhenceshould
beusedwithcautionifyouareobeseoraresufferingfromobesityrelateddisorders.
Infections—
UseofLevonorgestrel,especiallyforaprolongedduration,mayincreasethechancesof
gettinganinfection.Anyinstanceofinfectionafteruseofthismedicineshouldbe
reportedtothedoctor.
Allergies—
Tellyourdoctorifyouhaveeverhadanyunusualorallergicreactiontothismedicineor
anyothermedicines.Alsotellyourhealthcareprofessionalifyouhaveanyothertypes
ofallergies,suchastofoods,dyes,preservatives,oranimals.Fornon-prescription
products,readthelabelorpackageingredientscarefully.

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Otherdiseases—
Reporttheincidenceofdiseaseslikeasthma,epilepsy,migraine,diseasesoftheheart
andbloodvesselsetctothedoctorbeforereceivingthismedicine.
Othermedicines—
LevonorgestrelCAS:797-63-7isknowntointeractwithmanymedicinesthatyoumight
possiblybetaking.Reporttheuseofallmedicinesincludingherbsandsupplementsto
thedoctor