Life Science CELL DIVISION PROCESSMitosis.pdf

Mitosis

1. MITOSIS
CELL DIVISION
GRADE 10

2. OBJECTIVES (At the end of the lesson you
will be able to:
1. KNOW WHAT IS MITOSIS
2. LABEL STRUCTURE OF A CHROMOSOME
3. PROVIDE FUNCTIONS AND THE IMPORTANCE OF MITOSIS
4. NAME 4 STAGES OF MITOSIS

3. WHAT IS MITOSIS?

4. MITOSIS
A process where a cell divides into 2
identical daughter cells from a parent
cell.
It consists of 4 stages or phases namely:
Interphase, Prophase, Metaphase,
Anaphase and Telophase
It occurs to all eukaryotic organisms

5. MITOSIS
(Structure of a
chromosome)

6. Four Stages of
MITOSIS

7. INTERPHASE (the preparatory stage)

8. PROPHASE (stage 1)
THE CHROMATIN NETWORK CONDENSE TO
FORM CHROMOSOMES
THE NUCLEAR ENVELOPE DISAPPEARS
CHROMOSOMES CONSIST OF SISTER
CHROMATIDS HELD TOGETHER BY A
CENTROMERE
SPINDLE FIBRE ARE FORMED
CENTRIOLES APPEAR

9. METAPHASE (stage
2) M-middle
CHROMOSOMES ALIGN ALONG THE MIDDLE
OF THE CELL
HELD BY SPINDLE FIBRE IN POSITION

10. ANAPHASE (stage 3)
A-apart
BY THE HELP OF SPINDLE FIBRE,
CHROMOSOMES MOVE APART
CHROMOSOMES MOVE APART TO OPPOSITE
POLES(CENTRIOLES)

11. TELOPHASE (stage
4) T-tear apart
CHROMOSOMES UNCOIL
NUCLEOLI AND NUCLEAR
ENVELOPE/MEMBRANE REAPPEARS
SPINDLE FIBRE DISAPPEAR
OFTEN DESCRIBED AS REVERSE PROPHASE

12. IMPORTANCE OF MITOSIS
ASSIST IN REPAIRING DAMAGED CELLS AND TISSUES
IMPORTANT FOR GROWTH
IMPORTANT FOR REGENERATION OF LOST PARTS IN SPECIFIC ANIMALS
IMPORTANT FOR EMBRYONIC DEVELOPMENT
OCCURS ONLY IN SOMATIC/BODY CELLS

13. FULL MITOSIS PROCESS

14. REFERENCES
McIntosh, J. R., Molodtsov, M. I., & Ataullakhanov, F. I. (2012). Biophysics of
mitosis.Quarterly reviews of biophysics,45(2), 147-207.
McIntosh, J. R. (2016). Mitosis.Cold Spring Harbor perspectives in biology,8(9),
a023218.
Nicklas, R. B. (1971). Mitosis.Advances in cell biology, 225-297.
Wieser, S., & Pines, J. (2015). The biochemistry of mitosis.Cold Spring Harbor
perspectives in biology,7(3), a015776.