LIV.52 DS ROLE DISCUSSION............pptx

HIMALAYA

1. Himalaya Wellness Company

2. Wellness in every home, Happiness in every heart!

3. Hepato-protective herbs in Liv.52

4. Himsra ( Capparis Spinosa ) Contains p-methoxy benzoic acid Potent hepato-protective activity against drug induced hepatotoxicity. Protective action on histological architecture of liver.

5. Kasani ( Cichorium intybus ) It contains esculetin which is effective in chemically induced hepato-toxicity . It has potent antioxidant, free radical scavenging action.

6. It is known to have good antioxidant hepatoprotective properties. It decreases the elevated biochemical parameters. Protects DNA against oxidative damage Kakamachi ( Solanum nigrum )

7. Kasamarda ( Cassia occidentalis ) Has anti-microbial properties comparable to those of standard reference antibiotics. It modulates hepatic enzymes to provide hepatoprotection

8. Arjuna ( Terminalia arjuna ) Arjunolic acid and flavonoids present in this increase the natural antioxidant levels by increasing the glutathione content of liver cells. It has anti-lipid peroxidative action.

9. Jhavuka ( Tamarix gallica ) Inhibits free radical mediated DNA Damage. It has salutary effect on liver glycogen and serum proteins.

10. Bhumyaamlaki ( Phyllanthus amarus ) It has a nti viral properties. Blocks DNA polymerase, the enzyme needed for the replication of virus

11. Punarnava ( Boerhavia diffusa ) Himalaya Wellness Company It has anti -inflammatory, diuretic and tonic properties. Effective in jaundice and ascites.

12. Viral Hepatitis Loss of appetite & Suboptimal growth Alcoholic Liver damage Clinical Relevance

13. Viral Hepatitis

14. Facilitates rapid elimination of acetaldehyde & helps restore liver functions Alcohol Induced Liver Damage

15. Number of Clinical Trials 4 Number of Subjects 155 Age Range 18-75 Gender ration: Male/ Female 78-77 Dose regimen Two tablets, orally, twice daily Treatment duration 2-3 months

16. Exhibits salutary effects on liver Established efficacy in NAFLD

17. Modulates lipotropic activity Established efficacy & safety in NASH

18. In Management of Liver diseases caused by Diabetes

19. Also as an adjuvant with ATT , statins, chemotherapyantiretroviral drug As a supportive treatment during hemodialysis Liv.52 DS - Indications

20. Liv.52 DS Syrup 1 to 2 TSF b.i.d. Liv.52 DS Tablets 1 to 2 Tablets b.i.d. Liv.52 DS - Dosage

21. Thank you!