Lymphatic Filariasis Presenter: Dr. Soppimath Anusha Moderator: Dr. Blessy Babu 1
Evolution of lymphatic filariasis control programme in India 2
Evolution Filaria control in India : First pilot project – Odisha - 1949 – 1954 Three strategies used: i . Five day mass Diethylcarbamazine (DEC) therapy ii. Indoor residual spray in rural areas iii. Anti-larval measures in urban areas 3
Govt of India launched - 1955 – National Filaria Control Programme under National Institute of Communicable Diseases Objectives : i . To delimit the problem ii. To undertake large scale pilot iii. To train the professional and ancillary personnel required for the programme Strategies : Mass therapy at a dose of 4 mg/kg body weight for five consecutive days Three rounds of indoor residual spray in rural areas Weekly anti-larval measures in urban areas 4
Reviews and assessment: 1961 Recurrent anti-larva measures New control units Adequate waste disposal 1971 Detection and treatment Newer areas to be given priority 1982 100% centre sponsored Integration with Primary Health Centres Post of District Filaria Officer Filaria unit – minimum of 20,000 people Research unit under NCID 1995 Eradication of burgia malayi infection Integrated vector control Antigen and DNA based detection of microfilaria Delimitation surveys 5
Pilot project for Mass Drug Administration GOI – 13 districts – 1996 Andhra Pradesh , Kerala, Tamil Nadu, West Bengal, Uttar Pradesh, Odisha and Bihar Single dose - Diethylcarbamazine (DEC) was administered – National Filaria Day 2002 – 31 districts - DEC and Albendazole implemented in some districts 2004 : National campaign of Mass Drug Administration (MDA) with DEC - launched in 202 districts. 2006 : Recommended DEC+Albendazole in country. 2007: MDA programme was further scaled up to cover all 256 districts 2013: Validation started through Transmission Assessment Survey (TAS) 2016: Integration with NDD campaign (Feb & Aug) 6
Accelerated plan to eliminate LF Goal : Elimination of lymphatic filariasis (LF) as a public health problem by 2020 Actions: 1. Enhance advocacy 2. Implement confirmatory mapping in uncertain areas Mini TAS – 9-13 years school children – Antigen prevalence 3. Communication and social mobilization Sanitation practices, hygiene, capacity building for drug administrators Communication at all levels 7
4. Enhanced MDA in all districts 2004 – 2017 – 256 endemic districts covered At least 5 rounds (DEC + ALB) over 5 years Minimum coverage 65% If after 6 rounds – high prevalence – operational problems NVBDCP monitors and supervises MDA implementation PHCs manage ADRs - Contact person – Directly observed treatment strategy 8
5. Innovative preventive chemotherapy strategies and supplementary measures BCC/IEC Triple drug therapy - Ivermectin + DEC + ALB DEC medicated salt Collaboration with National Deworming Programme 6.Strengthen monitoring and surveillance Transmission Assessment Surveys – 6-7 year olds Assessment of Microfilaria prevalence – since 2017 – Filaria Test Strips – Ag testing Conducted by Evaluation units - <20lakh population If TAS1 – then TAS 2 and TAS 3 9
7. Identify people with chronic disease Line listing Morbidity management and disability prevention 8. Quality care Minimum package care - acute episodes, management of lymphedema, Prevention of acute attacks and providing surgery for hydrocele District health Administration 9. Quality data management 10
Five Pronged Strategy 11
Mass Drug Administration Approach – House to house , Booth, Group Pre-MDA – training, IEC/BCC activities, microfilaria survey During MDA – drug administration on fixed day, mopping –up operation, management of side effects of drugs, supervision Dosage : single dose of DEC - 6mg per kg single dose of albendazole - 400 mg irrespective age and weight Post MDA- Review, report 12
Morbidity management and disability prevention Lymphoedema management – washing, prevention and cure of entry lesions, elevation of foot, exercise, proper footwear, management of acute attacks Surgical management of hydrocele due to LF – PHCs – diagnose cases needing surgical intervention – CHCs – hydrocelectomy 13
2004 : National campaign of Mass Drug Administration (MDA) with DEC - launched in 202 districts. 2006 : NTF recommended DEC+Albendazole in country. 2007 : MDA programme was further scaled up to cover all 256 districts WHO increased donation of Albendazole Medical colleges and ICMR/NCDC involved to assess Financial allocation increased to Rs. 50-60 cr per annum IEC/BCC intensified under overall NHM 2013 : Validation started through Transmission Assessment Survey (TAS) 2016 : Integration with NDD campaign (Feb & Aug) 2018 : 10 th GALEF meeting held & launched Accelerated Plan of Elimination of Lymphatic Filariasis (APELF) 2018 : Triple Drug Therapy (IDA) i.e. DEC + Albendazole + Ivermectin in scheduled districts in phase wise manner. 2019 : Revision of financial norms for morbidity management of Lymphoedema Patient from Rs. 150 to Rs. 500 2020 - Expansion of IDA (Domestic procurement of Ivermectin) 2021 – Introduction of Block Level Strategy 2022 - LF Symposium held on 13th January 2023 with launch of Strategic Action Plan and Mega launch of bi-annual MDA 14