Malignant malenoma

detail description of malignant melanoma

1. MALIGNANT
MELANOMA
Ms. SAHELI C
LECTURER
IACN

2. INTRODUCTION
•Malignant melanoma accounting for about 3 to 4 % of all
diagnosed skin cancers.
•Melanoma begins in the melanocytescells within the
epidermis that give skin its colour.
•The incidence is rising by 3% a year.
•Melanoma is a cancer of melanin producing cells.
•It can arise from skin, mucosa of oropharynx, nasopharynx,
proximal esophagus, anorectum, female genitalia, eyes,
retina, uvea, leptomeninges(arachnoidparameter).

3. DEFINITION
•Melanoma, the most serious type of skin cancer, which
develops in the cells (melanocytes) that produce
melanin —the pigment that gives the skin its colour.
•Melanoma can also form in the eyes and rarely inside
of the body such as nose or throat.

9. RISK FACTORS FOR MELANOMA
•Large numbers of benign naevus.
•Clinically atypical naevus.
•Severe sunburn.
•Early years in a tropical climate.

20. DIAGNOSTIC EVALUATION

30. MANAGEMENT
•Complete surgical resection.
•In patients with recurrent disease and without
distant disease, a second surgical procedure is
considered as the best option.
•Malignant melanoma has been regarded as a
radio resistant tumour, radio therapy has
become utilized as adjuvant treatment
considering the tumour heterogeneity.
•No systemic therapy has been recognized as
effective for metastatic mucosal melanoma