MAMMOGRAPHY -INDICATIONS
Screening of asymptomatic women.
Screening of high risk women.
Follow up of patients after mastectomy of same and opposite breast / same breast with implant
Investigations of benign breast diseases with eczematous skin,nipple discharge , skin thickening .
Investigation of a breast lump.
Investigation of occult primary with secondaries .
Male breast evaluation .
TYPE OF MAMMOGRAPHIC EXAMINATION
Diagnostic mammography
Is performed on patients with symptoms or elevated risk factors.
Two or three viewsof each breast may be required.
Screening mammography
Is performed on asymptomatic women with the use of a two view protocol,
usually medial lateral oblique and cranio caudal , to detect on unsuspected cancer
MAMMOGRAPHY -BASICS
Uses low-energy x-rays (40kVp) for dectecting breast pathologies.
Higher kV -Poor Contrast
Lower kV -Good Contrast
Tissues within breast have verysmall difference inattenuation property-Lacks contrast
<40kVp -Good photoelectric effect-brings out contrast between the tissues within the breasts.
Better contrast
Better detailing of structures
INSTRUMENTATIONS
HIGH FREQUENCY X-RAYGENERATOR
X-RAY TUBE
ANODE
CATHODE
BEAM PORT
K-EDGE FILTERS
COMPRESSION PADDLE
SPOT COMPRESSION
PARALLEL LINEAR GRID
IMAGE RECEPTOR
AEC (AUTOMATIC EXPOSURE CONTROL)
ANODE (TARGET)
Usually-Tungsten (xray /Floro/ CT/ cathlab)
MOLYBDENUM -17.5 &19.6 keV
RHODIUM-20.2&22.7 keV
CHARACTERISTIC RADIATION
Characteristic x-ray Characteristic x-rays are produced after ionization of a k-shell electron. When an outer-shell
electron fills the vacancy in the k shell, an x-ray is emitted.
In mammography, 17.5-19.5kev characteristic x-ray is produced with Mo and 23kev is produced with Rh
ANODE ANGLE = 16°to0to -9°
EFFECTIVE ANODE ANGLE
-Angle of anode relative to the horizontal tube mount
XRAY TUBE TILT
-To reduceunwanted radiation
-focus only to the breast area
SOURCE TO IMAGE DISTANCE (SID)
-lesser than usual Radiography -60/65 cm(Chest = 18)
-short SID
-Heel Effect utilized
AtCathode→chestwall–Thicker tissues
SIDE
AtAnode→Nippleregion–Less Thickness
SIDE
Non-uniformityofX-ray Intensity
Along the cathode side -MoreIntensity
Along the Anode side-Less Intensity
PARTS OF MAMMOGRAPHY EQUIPMENT
Beam port-1 mm Beryllium
Since metal/ Glassisused in XRAY TUBE
metal will absorb the low energyphotonsfrom xray tube
K-edge filters-Cuts unwanted Lowenergy photons (RADIATION)
/High energy photons (SCATTER –Reduces contrast)
(0.03mm Mo / 0.025mm Rh)
PARTS OF MAMMOGRAPHY EQUIPMENT
To decreaseBreast thickness,spreadsout the tissue
-Spreads outsuperimposedanatomy.
Scatter Radiation- contrast
Radiation doseto the breast tissue
Geometric Blurring (closer to imagereceptor)
Decreases the kinetic blur .
Makes breast thickness uniformin film density.
Differentiatesthe easily compressible cysts and fibro-
glandular tissue from the more rigid carcinomas
Separatesthe super imposed breast lesions .
Compression paddle
PARTS OF MAMMOGRAPHY EQUIPMENT
GRIDS
Stationary grids or grids placed in between the screen and the film are no longer used as the thin grid lines
compromised on the quality of the image .
Covered tiny details such as microcalcifications
Hence oscillating grids are used o Grid ratio of 4 : 1 or 5 : 1
The grid lines are eliminated by the motionof the grid .
Grids improve the image quality and cause a significant reduction
PARTS OF MAMMOGRAPHY EQUIPMENT
Spot.compression -for imaging particular region
Parallel Linear grid-(4:1 to 5:1) low grade ratiogridsused
to increase theContrast
Image Receptor
Screen film
CR Cassette
Flat paneldetector -(Digital Mammography)
AEC-Automatic Exposure Control
KeV selected →MAS automatically chosen.
FLAT PANEL DETECTORS -INDIRECT
Indirect Amorphous silicon technology
Xray scintillator(Gradoliniun Sulphate / Csl)
Produceslightflashes when Xraybeam falls overit.
Silicon Photodiode array(Photo detector)
Made of Amorphous silicon
Converts light photonsfrom the scintillatorinto electrical signal
TFT-electronic switch
-Reads electrical signal
-Gives positional information
-This data is sent to AEC(Analogue toDigitalConverter)
AEC
Converts it into digital signaland are finally sent to Computerfor processing
Disadvantage-LIGHT SCATTER
Scattering oflight within the phosphors leading to unsharpness
FLAT PANEL DETECTORS -DIRECT
Crystals of amorphousselenium
directly converts Xrays intoelectricalsignal that is stored in a capacitor (ready to be read)
MAGNIFICATION TECHNIQUE
Toincreasethe visibility of finer details like microcalcification
Increase O ID -object to Image Distance
Breast is kept over a raised platform
No need for grid as there is presence of air gap
SCREEN FILM MAMMOGRAPHY
Old method
The image is created directly on a film-Non modifiable
Less sensitive for women with dense breasts
Screen film cassette used
Single emulsionfilm
Single screen
Terbium activated Gadoliniumoxysulphide
Screen emits green light
Film will be sensitive to greenlight(ORTHOCHROMATIC FILM)
COMPUTER RADIOGRAPHY (CR) MAMMOGRAPHY
A/K/A Filmless radiography
Electronic radiography
Digital storage phosphor imaging
Xray images are acquired in digital format
Photostimulable phosphor plates used
Imaging plate has high sensitivity to xrays
COMPONENTS
storage phosphor cassette
Storage phosphor reader
Bar code scanner
Workstation
Photostimuliable Phosphor (PSP) Cassette
PSPReceptormaterials
. BaFBr : Eu2+
. BaF (Br1): Eu2+
.Ba SrFBr: Eu 2+
DIGITAL MAMMOGRAPHY
Also called full-field digital mammography (FFDM)
-in which the x-ray film is replaced by electronics that convert x-rays into mammographic pictures of the breast.
Display Monitor-HIGH RESOLUTION (5 MP)
Direct Digital Mammography
-Flat panel detector with amorphous seleniumarray
Indirect Digital Mammography
-Flat panel scintillator with amorphoussilicon diode array
DIGITAL MAMMOGRAPHY
ADVANTAGE
Better contrast, more details.Better delineation of parenchyma & subcutaneous tissue
Better noise level reduction
Tolerance to over/under exposure (Avoids Repetition?
Post-processing techniques for better diagnosis
Radiation dose isdecreased-Mean glandular dosein mammography
Screen Film(2-3m bGy)
Digital (20-30% reduction)
Image can be seen quickly andstored digitally(less storage space )
LIMITATIONS OF 2D MAMMOGRAPHY
20%of cancers will be missed
10% recalled for additional workup
75-80% of biopsies result in benign lesions
sensitivity decreases with increased breast density
2D mammograms, take images only from the front and side, this may create images with
overlapping breast tissue
ADVANCES IN DIGITAL MAMMOGRAPHY
Computer-Aided Diagnosis
-usessoftware to detect area of clinicalsignificance andhighlightthemfor better output image
Digital Breast Tomosynthesis(DBT)
Xray Tube rotates /moves in a 50-55°arcaround the breast,
capturing several (11-25)low dose projections of the breast at different angles.
Then reconstructed to 3DProjection images (1 mm slices)
3D MAMMOGRAPHY
DIGITAL BREAST TOMOSYNTHESIS-DBT (3D MAMMOGRAPHY )
Disadvantages of DBT
•Twice the radiation compared to 2D mammo
•More storage requirements
•Takes longer time to read
•Cannot be read on demand
Advantages of DBT
•Increased cancer detection rate
•Lesions are better defined
•Precise location of lesions
•Less false positive recalls
3D MAMMOGRAPHY
HOW MAMMOGRAM IS PERFORMED ?
HOW MAMMOGRAM IS PERFORMED ?
CRANIO CAUDAL (CC VIEW)
demonstrate maximum tissue on both medial and lateral
aspects of the breast with the retromammary space and some
pectoral muscle
The following points were analyzed on CC view:
nipple should be in profile
nipple should point straight and should not be pointing lateral
or medial
PND (pectoral nipple distance) must be within 1 cm of the
same measurement of the MLO view.
HOW MAMMOGRAM IS PERFORMED ?
MEDIOLATERAL OBLIQUE(MLO VIEW)
demonstrate axilla, axillary tail, and inframammary
fold with all the breast tissue
The following points were analyzed on MLO view:
Breast should be pulled out with nipple in profile
The pectoralis muscle margin should be well visualized
The lower edge of pectoralis muscle should be at the level
of pectoralis–nipple line (PNL) or below
PND must be within 1 cm of the same measurement of
the MLO view.
When MLO image of both breasts are viewed as mirror
images, pectoralis muscle should meet in the midline and
form a “V”.
OTHER VIEWS
Latero-medial (LO) -from the outside towards the center
Medio-lateral (ML) -from the center towards the outside
Spot compression -compression on only a small area, to get more detail
Cleavage view -both breast compressed, to see tissue near the center of
the chest
Magnification -to see borders of structures and calcifications
REPORTING A MAMMOGRAM
Breast Imaging Reporting and Data System (BI-RADS)
RISK ASSESSMENT AND QUALITY ASSURANCE TOOL developed by American college of radiology (ACR)
that provides a widely accepted lexicon and reporting schema for imaging of thebreast.
All mammographic, ultrasound and breast MRI findings and reports should closely adhere to the BI-RADS lexicon
and assessment categories.